Big Pharma’s R&D spending flatlined in 2022: What it means for the industry —Bluebird Bio submits BLA for sickle cell disease gene therapy—Eli Lilly launches Mounjaro head-to-head trial against Novo Nordisk's Wegovy-- See more on our front page news http://bit.ly/w28kSd #bigpharma #researchanddevelopment #bluebirdbio #sicklecelldisease #genetherapy #obesity #elililly #novonordisk #wegovy #mounjaro #clinicaltrials #pharma #pharmanews #biotech #biopharma #biotechnology #cafepharma
#bigpharma #researchanddevelopment #bluebirdbio #Sicklecelldisease #genetherapy #obesity #elililly #novonordisk #wegovy #mounjaro #clinicaltrials #pharma #pharmanews #biotech #biopharma #biotechnology #cafepharma
People with #SickleCellDisease who receive nonmyeloablative #StemCellTransplants are at greater risk for developing new tumors, according to a new study published in the Journal of Clinical Oncology. https://t.co/w4ejLCh7i1
#Sicklecelldisease #stemcelltransplants
A Novel Measure of #Pain Location in Adults with #SickleCell Disease https://discovery.researcher.life/article/a-novel-measure-of-pain-location-in-adults-with-sickle-cell-disease/aa81211c60693dc9b18df2516c25486c
#SickleCellPainCrisis #SickleCellDisease #SickleCellAnemia
#health #Blood #BloodDisorders #science #medicine
#BlackMastodon #BlackFedi
@blackmastodon@a.gup.pe
@BlackMastodon@chirp.social
#pain #SickleCell #sicklecellpaincrisis #Sicklecelldisease #sicklecellanemia #Health #blood #blooddisorders #Science #medicine #BlackMastodon #BlackFedi
What is BioGPT and what does it mean for healthcare? — Do mass tech layoffs mean the same for biopharma? —Vertex teases launch of landmark CRISPR therapy -- See more on our front page news http://bit.ly/w28kSd #artificialintelligence #ai #biogpt #microsoft #layoffs #vertexpharma #crispr #sicklecelldisease #pharma #pharmanews #biotech #biopharma #biotechnology #cafepharma
#artificialintelligence #ai #biogpt #microsoft #layoffs #vertexpharma #crispr #Sicklecelldisease #pharma #pharmanews #biotech #biopharma #biotechnology #cafepharma
Roche, Boehringer tap biosensor firms for patient studies — FDA advisers back Cidara and Melinta’s antifungal treatment — EMA validates Vertex's CRISPR application, clearing barrier on road to landmark approval -- See more on our front page news http://bit.ly/w28kSd #roche #boehringeringelheim #biosensors #fda #antifungals #crispr #sicklecell #sicklecelldisease #pharma #pharmanews #biotech #biotechnology #biopharma #cafepharma
#roche #boehringeringelheim #biosensors #FdA #antifungals #crispr #sicklecell #Sicklecelldisease #pharma #pharmanews #biotech #biotechnology #biopharma #cafepharma
@gcbias
Some #FoodForThought from the #researchpaper linked above💡💡💡
“Importantly, in my view, the term ‘genetically similar to’ also helps to avoid the assumption of homogeneity within labels; ‘similar to’ does not imply ‘same as’. Similarity-based sample descriptors also move us some way to acknowledging the continuous nature of #geneticvariation across #humangroups in our sample descriptions. I am more genetically similar to some samples than I am to others, but that does not imply that there are natural groupings. Nor do similarity-based labels imply how I, as an individual, might choose to identify or what distribution of environments I might experience. For example, a person may be genetically similar to 1000 #Genomes samples labeled Southern Asian, yet in itself this similarity does not identify them as Southern Asian, whereas stating that a person has ‘Southern Asian #geneticancestry ’ comes much closer to making that linkage in people’s minds.
Working out the #genealogicalhistory of individuals and of groups of people from around the world is a fascinating area of research, but it should not be the day job of the majority of researchers in the field of #humangenetics , who instead need accurate sample descriptors of current day #geneticdiversity that aid clear communication.”
END OF EXCERPT
~
Adding colour to #discourse with this screenshot attachment and link. Extraordinary future ahead in the field of human genetics and #humanidentity, in general. #TheLancet #AmbroiseWonkam #johnhopkinsuniversity #schoolofmedicine #geneticvariation #geneticmedicine #MckusickNathansInstituteofGeneticMedicine
https://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(22)00880-7.pdf
https://doi.org/10.1016/S0140-6736(22)00880-7
Related
#AfricanGenomeVariationProject
#1000genomesproject #GhanaianGenome #OforiAcquah #geneticcounselling #yemaachibiotech #yemaachi #genomicdataset #Sicklecelldisease #malaria
#SarsCoV2 #researchgate
#geneticdata #geneticdisease #ethnicity #populationdescriptors #racialmakeup #racialclassification #ethnicclassification #nationalacademiesofsciencesengineeringand #biomedicalresearch #rx #med #ethnicorigins #dei #biodiversity #bloodbank #organdonor #geneticlandscapes #socialdeterminantsofhealth #clinicalgenetics #therapeutics #diagnostics #treatments #ancientdna #genealogy #nondarwinian #demography #demographics #polygenics #nationalinstitutesofhealth #nih #medicine #geneticancestor #humangenetics #biomedicine #biomed #racialidentity #ancestralidentity #culturalidentity #crt #criticalracetheory #anthropology #biobank #23andme #familytree #familyheritage #ancestralheritage #commonancestor #biomedical #populationbiology #geobiologie #geobiology #geneticmapping #blooddonor #blooddonation #populationhealth #admixedancestry #phenotype #phenotypingdata #phenotypedata #americanjournalofhumangenetics
#foodforthought #researchpaper #geneticvariation #humangroups #genomes #geneticancestry #genealogicalhistory #humangenetics #GeneticDiversity #discourse #humanidentity #thelancet #ambroisewonkam #johnhopkinsuniversity #schoolofmedicine #geneticmedicine #mckusicknathansinstituteofgeneticmedicine #africangenomevariationproject #1000genomesproject #ghanaiangenome #oforiacquah #geneticcounselling #yemaachibiotech #yemaachi #genomicdataset #Sicklecelldisease #malaria #SarsCoV2 #researchgate #geneticdata #geneticdisease #ethnicity #populationdescriptors #racialmakeup #racialclassification #ethnicclassification #nationalacademiesofsciencesengineeringand #biomedicalresearch #rx #med #ethnicorigins #dei #biodiversity #bloodbank #organdonor #geneticlandscapes #socialdeterminantsofhealth #clinicalgenetics #therapeutics #diagnostics #Treatments #AncientDNA #genealogy #nondarwinian #demography #demographics #polygenics #nationalinstitutesofhealth #nih #medicine #geneticancestor #biomedicine #biomed #RacialIdentity #ancestralidentity #culturalidentity #crt #criticalracetheory #anthropology #biobank #23andme #familytree #familyheritage #ancestralheritage #commonancestor #biomedical #populationbiology #geobiologie #geobiology #geneticmapping #blooddonor #blooddonation #populationhealth #admixedancestry #phenotype #phenotypingdata #phenotypedata #americanjournalofhumangenetics
Nature Medicine asked 11 leading researchers for their top clinical trials to watch in 2023. The replies include #exenatide in #Parkinsonsdisease - the most prominent and promising Phase III #drugrepurposing trial in recent years -, autologous CRISPR–Cas9-modified CD34+ human stem and progenitor cells for #sicklecelldisease; and there should be more substantial data on #lecanemab for #Alzheimers disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798349/
#alzheimers #lecanemab #Sicklecelldisease #drugrepurposing #parkinsonsdisease #exenatide
RT @Satyayadav__@twitter.com
#Hydroxyurea an effective, low cost and well tolerated drug for sickle patients and yet under-utilised globally for prevention of Stroke in #sicklecelldisease #ASH22
Hydroxyurea should be made available to all sickle cell disease patients globally
Let’s get basics right ! https://twitter.com/dukesickle/status/1601682347803697153
🐦🔗: https://twitter.com/Satyayadav__/status/1601805887298973696
#hydroxyurea #Sicklecelldisease #ash22
RT @majorajay@twitter.com
8. 582 @lillian_meacham@twitter.com: Sexual function post-HSCT for #sicklecelldisease. Interest in sexual activity lower in women, but within normal PROMIS range. 1/3 women & 2/3 men did not know infertility risk (!!!). Would love to see content validation. #ASH22
🐦🔗: https://twitter.com/majorajay/status/1601559442620678144
RT @NHLBI_BLOODDir@twitter.com
Cold weather can trigger a pain crisis for people living with #SickleCellDisease. By studying mechanisms that lead to this response, including the role of #complement, an ancient part of the immune system, researchers aim to inform future treatment: https://bit.ly/3ueWXZx #ASH22
🐦🔗: https://twitter.com/NHLBI_BLOODDir/status/1601675647469985792
#Sicklecelldisease #complement #ash22
RT @NHLBI_BLOODDir@twitter.com
At #ASH22, pediatric researchers will discuss early studies to assess the use of intravenous forms of arginine, an amino acid that supports blood flow and immune function, to potentially alleviate severe #SickleCellDisease pain crises: https://bit.ly/3XRrWIH
🐦🔗: https://twitter.com/NHLBI_BLOODDir/status/1601592628386185219
I see they're also working to apply this tech in #SickleCellDisease as well!
RT @PCANAD_APIIOA@twitter.com
Want to learn abt #SickleCellDisease? Scan the QR code below to register for the upcoming webinar @PCANAD_APIIOA@twitter.com @CACBNBC@twitter.com @obnn2021@twitter.com @NSBlackNurses@twitter.com @canadanurses@twitter.com @CFNU@twitter.com @CASN43@twitter.com @LeighChappy@twitter.com @Bukky_ibitoye@twitter.com @CanadasLifeline@twitter.com
Proudly supported by @sicklecellca@twitter.com @biba_tinga@twitter.com #OpenToAll!
🐦🔗: https://twitter.com/PCANAD_APIIOA/status/1592567445356974080
Looking for more Clinically Vulnerable people / households on Mastodon.
Please add more # s to help us! 🙏 & ♻️
#Downs #DownsSyndrome
#Leukaemia #Lymphoma
#SickleCell #SickleCellDisease
#ChronicKidneyDisease #CKD
#LiverDisease
#OrganTransplants #KidneyTransplant #HeartTransplant #LungTransplant #LiverTransplant #PancreasTransplant
#BoneMarrowTransplant
#Autoimmune #Inflammatory
#Rheumatoid #Arthritis
#InflammatoryBowelDisease #IBD
#HIV #AIDS
2/
#aids #hiv #ibd #inflammatoryboweldisease #arthritis #rheumatoid #inflammatory #autoimmune #bonemarrowtransplant #pancreastransplant #LiverTransplant #lungtransplant #hearttransplant #kidneytransplant #organtransplants #liverdisease #CKD #ChronicKidneyDisease #Sicklecelldisease #SickleCell #lymphoma #leukaemia #DownsSyndrome #downs