RT @AW_NGS
We have come a long way since 2012 for the tomato 🍅 Heinz 1706 genome. From 22,524 contigs down to 12 T2T contigs with only rDNA repeat unresolved. #AGBTAg23 #nanopore #T2T Great collaboration!

RT @AW_NGS
@sergekoren showing @nanopore duplex accuracy generated by @KeyGeneInfo reaching 99.9% identity for 🍅, on par with HiFi but with significant longer read lengths. #AGBTAg #agbtag23 #T2T

RT @AW_NGS
Automated Telomere-To-Telomere crop genome assembly using only @nanopore sequencing presented at international conferences; http://www.keygene.com/t2t-assemblies #AGBTAg #nanoporecomf #T2T

RT @nanopore@twitter.com

KM: The human genome is finally complete. This is because of a step change in technology as well as the work of the #T2T. We can access regions of the genome we couldn't before. #nanoporeconf

🐦🔗: https://twitter.com/nanopore/status/1600148533964701696

Worth adding a little on the population genetics of the new complete human Y chr.
(By @erikl861@twitter.com, @Josh_Lipson@twitter.com, and @leorcooper@twitter.com).

The haplogroup of the new reference Y sequence is J-L816. It appears in about 5% of Ashkenazi Jews and is rare elsewhere.

RT @aphillippy@twitter.com

"The complete sequence of a human Y chromosome" ✅ thanks to @ArangRhie@twitter.com @sergeynurk@twitter.com et al! #T2T 🧵 https://www.biorxiv.org/content/10.1101/2022.12.01.518724v1

🐦🔗: https://twitter.com/aphillippy/status/1598654803072077824

RT @aphillippy@twitter.com

"The complete sequence of a human Y chromosome" ✅ thanks to @ArangRhie@twitter.com @sergeynurk@twitter.com et al! #T2T 🧵 https://www.biorxiv.org/content/10.1101/2022.12.01.518724v1

🐦🔗: https://twitter.com/aphillippy/status/1598654803072077824

RT @aphillippy@twitter.com

"The complete sequence of a human Y chromosome" ✅ thanks to @ArangRhie@twitter.com @sergeynurk@twitter.com et al! #T2T 🧵 https://www.biorxiv.org/content/10.1101/2022.12.01.518724v1

🐦🔗: https://twitter.com/aphillippy/status/1598654803072077824

RT @StevenSalzberg1@twitter.com

Terrific work by @ArangRhie@twitter.com, @aphillippy@twitter.com, and a large supporting case to assemble and annotate the first truly complete human Y chromosome. (This Y sequence is already in the #T2T complete human genome; this new paper gives all the details) https://www.biorxiv.org/content/10.1101/2022.12.01.518724v1

🐦🔗: https://twitter.com/StevenSalzberg1/status/1598681831997464577

RT @aphillippy@twitter.com

"The complete sequence of a human Y chromosome" ✅ thanks to @ArangRhie@twitter.com @sergeynurk@twitter.com et al! #T2T 🧵 https://www.biorxiv.org/content/10.1101/2022.12.01.518724v1

🐦🔗: https://twitter.com/aphillippy/status/1598654803072077824

RT @aphillippy
The #T2T team is excited to release our first draft of a complete, diploid human genome for the @GenomeInABottle benchmark sample, HG002! Links to the data and assembly can be found here: https://github.com/marbl/hg002 🧵

RT @aphillippy@twitter.com

The #T2T team is excited to release our first draft of a complete, diploid human genome for the @GenomeInABottle@twitter.com benchmark sample, HG002! Links to the data and assembly can be found here: https://github.com/marbl/hg002 🧵

🐦🔗: https://twitter.com/aphillippy/status/1590792420731473922

That's awesome, thanks for this major effort!
---
RT @aphillippy
The #T2T team is excited to release our first draft of a complete, diploid human genome for the @GenomeInABottle benchmark sample, HG002! Links to the data and assembly can be found here: https://github.com/marbl/hg002 🧵
https://twitter.com/aphillippy/status/1590792420731473922

#人類基因組 #genome
#基因 #DNA

quote :
本周，《科学》杂志同时上线的6篇论文中，一个名为“ #端粒到端粒 ”联盟（#T2T）的国际科研团队宣布完成了最新的人类参考基因组（被命名为T2T-CHM13），包括所有22条常染色体和X染色体的无缝组装。

https://mp.weixin.qq.com/s/gGNMS0d2j8tZQrkzL566sw