Happy to report our review in Current Atherosclerosis Reports!
#Telomere Length: Implications for Atherogenesis
by me & my supervisor Dr. J. Geoffrey Pickering
TL as a biomarker & causal factor for ASCVD
Evidence from seminal studies, incld #UKBiobank #TOPMed
https://link.springer.com/article/10.1007/s11883-023-01082-6
https://www.nature.com/articles/s41588-022-01225-6 "Powerful, scalable and resource-efficient meta-analysis of #rareVariant associations in large whole genome sequencing studies" #wgs #genetics #genomics #bioinformatics #MetaSTAAR performs rare variant meta-analysis at scale and produces results comparable to using pooled data. We further demonstrate that MetaSTAAR is scalable to biobank-scale cohorts through meta-analysis of #TOPMed WGS data and #UKBiobank WES data of ~200,000 samples.
#rarevariant #WGS #genetics #genomics #bioinformatics #metastaar #TOPMed #ukbiobank
RT @mikelove@twitter.com
Very excited to see this work on #multiomic methods by @jiang_minzhi@twitter.com @yunliunc@twitter.com @RaffieldUNC@twitter.com et al, with the @nih_nhlbi@twitter.com #TOPMed consortium posted to @biorxivpreprint@twitter.com
"Uncovering Cross-Cohort Molecular Features with Multi-Omics Integration Analysis"
RT @mikelove
Very excited to see this work on #multiomic methods by @jiang_minzhi @yunliunc @RaffieldUNC et al, with the @nih_nhlbi #TOPMed consortium posted to @biorxivpreprint
"Uncovering Cross-Cohort Molecular Features with Multi-Omics Integration Analysis"
RT @mikelove@twitter.com
Very excited to see this work on #multiomic methods by @jiang_minzhi@twitter.com @yunliunc@twitter.com @RaffieldUNC@twitter.com et al, with the @nih_nhlbi@twitter.com #TOPMed consortium posted to @biorxivpreprint@twitter.com
"Uncovering Cross-Cohort Molecular Features with Multi-Omics Integration Analysis"