#TCells burn out just a few hours after encountering #cancer #tumors
https://arstechnica.com/health/2023/08/t-cells-burn-out-just-a-few-hours-after-encountering-cancer-tumors/
A clinical trial assessing a synthetic antibody to generate an immediate response and also generate a more durable treatment for solid tumor cancers, advanced to a mid-stage study.
https://sciencebusiness.technewslit.com/?p=45068
#News #Press #Science #Business #Cancer #Biotechnology #ClinicalTrial #Immunotherapy #AdverseEffects #CheckpointInhibitor #Antibody #ImmuneSystem #TCells #InnateImmuneSystem
#News #press #science #business #cancer #biotechnology #ClinicalTrial #Immunotherapy #adverseeffects #checkpointinhibitor #antibody #immunesystem #Tcells #innateimmunesystem
Really cool application of Infinity Flow to #MouseModel #Tcells, which allows readout/prediction of >200 surface epitopes on single cells via #FlowCytometry.
#mousemodel #Tcells #flowcytometry #immunology #tissueimmunity
Cool computational method for separating γδ #Tcells by #rna #sequencing
Rather than relying on paired #TCRseq or #CITEseq, they calculate module scores of TCR constant and variable regions
#Tcells #RNA #sequencing #tcrseq #citeseq
Engineered T-Cells Shown Safe, Reduce Myasthenia Gravis
Results of a small clinical trial show genetically altered T-cells from patients with myasthenia gravis are well tolerated and reduce symptoms of the disease.
https://sciencebusiness.technewslit.com/?p=44933
#News #Science #Business #MyastheniaGravis #Autoimmune #ClinicalTrial #Biotechnology #Tcells #Autologous
#News #science #business #myastheniagravis #autoimmune #ClinicalTrial #biotechnology #Tcells #autologous
Referenced link: https://medicalxpress.com/news/2023-06-family-resemblance-cells-coronaviruses.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-06-family-resemblance-cells-coronaviruses.html
Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1664362950440673281#m
RT by @physorg_com: Family resemblance: How #Tcells could fight many coronaviruses at once @ljiresearch @CellRepMed https://linkinghub.elsevier.com/retrieve/pii/S2666379123002070 https://medicalxpress.com/news/2023-06-family-resemblance-cells-coronaviruses.html
Clinical Trial Begins for Peanut Allergy Treatment
A clinical trial is underway testing an experimental therapy for #peanut #allergy that its developer says trains the #immune system without using peanut #proteins.
https://sciencebusiness.technewslit.com/?p=44849
#News #Science #Business #Biotechnlogy #ClinicalTrial #Immunology #TCells #Peptides #Chemistry #Allergens #Anaphylaxis #Australia
#peanut #allergy #immune #proteins #News #science #business #biotechnlogy #ClinicalTrial #immunology #Tcells #peptides #chemistry #allergens #anaphylaxis #australia
Precision T-Cell Solid Tumor Therapy Trial Underway
A clinical trial has begun testing a treatment for solid #tumor #cancers using engineered T-cells with proteins to attack specific tumor cells, but also avoid healthy cells.
https://sciencebusiness.technewslit.com/?p=44842
#News #Science #Business #ClinicalTrial #Biotechnology #Tcells #Immunotherapy #SolidTumor #PrecisionMedicine #CompanionDiagnostic
#tumor #cancers #News #science #business #ClinicalTrial #biotechnology #Tcells #Immunotherapy #solidtumor #precisionmedicine #companiondiagnostic
AI-Designed Cancer Vaccine Shown to Act Against Melanoma
Results of a small clinical trial show most patients with #melanoma receiving a personalized therapeutic #vaccine with an approved #immunotherapy reduced at least some of their #tumors.
https://sciencebusiness.technewslit.com/?p=44832
#News #Science #Business #Biotechnology #Cancer #PrecisionMedicine #Tcells #ArtificialIntelligence #Algorithms #ClinicalTrial #ASCO2023
#melanoma #vaccine #Immunotherapy #tumors #News #science #business #biotechnology #cancer #precisionmedicine #Tcells #artificialintelligence #algorithms #ClinicalTrial #asco2023
Referenced link: https://medicalxpress.com/news/2023-05-car-cells-prostate-cancer-bone.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-05-car-cells-prostate-cancer-bone.html
Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1653859490943365124#m
RT by @physorg_com: Researchers develop CAR #Tcells that fight #prostatecancer in bone @ScienceAdvances https://www.science.org/doi/10.1126/sciadv.adf0108 https://medicalxpress.com/news/2023-05-car-cells-prostate-cancer-bone.html
Referenced link: https://medicalxpress.com/news/2023-05-black-sheep-helper-cells-key.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-05-black-sheep-helper-cells-key.html
Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1653842193302339584#m
RT by @physorg_com: 'Black sheep' of helper #Tcells may hold key to precision allergy treatment @natimmunol https://www.nature.com/articles/s41590-023-01501-5 https://medicalxpress.com/news/2023-05-black-sheep-helper-cells-key.html
Low-Dose Covid-19 Vaccine Generates Strong Immune Response
Ultra-low quantities of an experimental Covid-19 #protein #vaccine delivered in synthetic cell components are shown in lab animals to generate strong #immune responses.
https://sciencebusiness.technewslit.com/?p=44731
#News #Science #Business #Biotechnology #Covid19 #SARSCoV2 #Preclinical #Exosomes #Nanoscale #ImmuneResponse #Antibody #TCells
#protein #vaccine #immune #News #science #business #biotechnology #COVID19 #SarsCoV2 #preclinical #exosomes #nanoscale #immuneresponse #antibody #Tcells
T-Cell Biotech Gains €17.5M in Grant, Equity Funds
A developer of engineered #immune cells to treat #cancer and immune deficiencies is raising €17.5 million ($US 19.1 million) in #equity and #grant funding from an #EU agency.
https://sciencebusiness.technewslit.com/?p=44643
#News #Science #Business #Biotechnology #Tcells #ImmuneSystem #Finance #Entrepreneurs #France #StemCells #SCID #Leukemia
#immune #cancer #equity #grant #eu #News #science #business #biotechnology #Tcells #immunesystem #finance #Entrepreneurs #France #stemcells #scid #leukemia
Referenced link: https://medicalxpress.com/news/2023-03-cells-human-blood-secrete-substance.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-03-cells-human-blood-secrete-substance.html
Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1641480673331478528#m
RT by @physorg_com: Study discovers #Tcells in #humanblood secrete a substance that affects blood pressure and inflammation @PNASNews https://pnas.org/doi/10.1073/pnas.2212476120 https://medicalxpress.com/news/2023-03-cells-human-blood-secrete-substance.html
Referenced link: https://medicalxpress.com/news/2023-03-cells-key-immune-therapies.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-03-cells-key-immune-therapies.html
Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1640747340230270977#m
RT by @physorg_com: Study: Keeping #Tcells active, but not too active, could be key to new immune therapies @Hudson_Research https://www.nature.com/articles/s41419-023-05619-0 https://medicalxpress.com/news/2023-03-cells-key-immune-therapies.html
Referenced link: https://medicalxpress.com/news/2023-03-cancer-lung-maneuvers-killer-cells.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-03-cancer-lung-maneuvers-killer-cells.html
Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1640623886445232128#m
RT by @physorg_com: #Cancer that spreads to the lung maneuvers to avoid being attacked by 'killer' #Tcells @MCG_AUG https://linkinghub.elsevier.com/retrieve/pii/S1535610823000338 https://medicalxpress.com/news/2023-03-cancer-lung-maneuvers-killer-cells.html
Antitumor T-cell function requires #CPEB4-mediated adaptation to chronic #endoplasmic #reticulum stress
Raúl Méndez and colleagues at IRB Barcelona show that RNA-binding protein CPEB4 mediates transient unfolded protein response #UPR for stress adaptation in #CD8 #Tcells
#cpeb4 #endoplasmic #reticulum #upr #cd8 #Tcells
Referenced link: https://medicalxpress.com/news/2023-03-discovery-cells-role-alzheimer-diseases.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-03-discovery-cells-role-alzheimer-diseases.html
Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1633534244067872768#m
RT by @physorg_com: Discovery of #Tcells' role in Alzheimer's, related diseases, suggests new treatment strategy @WUSTLmedschool @nature https://www.nature.com/articles/s41586-023-05788-0 https://medicalxpress.com/news/2023-03-discovery-cells-role-alzheimer-diseases.html
#Innate and #Adaptive #Immunity during SARS-CoV-2 Infection: Biomolecular Cellular Markers and Mechanisms
#COVID19 #Bcells #neutrophils #dendritic_cells #Tcells #NKcells #monocytes #macrophages #SARSCoV2
https://www.mdpi.com/2076-393X/11/2/408
#innate #adaptive #immunity #COVID19 #Bcells #Neutrophils #dendritic_cells #Tcells #NKcells #monocytes #macrophages #SarsCoV2
Latest curated articles👇🏽
📰Resident memory #Tcells develop regional dialects (📷)
📰Genetic #variants and cellular function & disease
💅🏽#DNA damage & somatic mutations in mammalian cells after irradiation with a nail polish dryer
🔗http://biomed.news/bims-nimamd/2023-01-22
🙏🏽Thx @Bims_BiomedNews@twitter.com