.@AnnaOsnato &co explore a #PLOSBiology study which reveals a previously undefined group of cells in the early human #embryo that diverges from the main lineages & undergoes apoptosis through the activity of young #TransposableElements https://plos.io/3CHIA45

Referenced link: https://phys.org/news/2023-05-prevalence-transposable-elements-clues-worldwide.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-05-prevalence-transposable-elements-clues-worldwide.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1653078311235469321#m

Prevalence of #transposableelements may provide clues to worldwide #mammal biodiversity @stonybrooku @sciencemagazine https://www.science.org/doi/10.1126/science.abn1430 https://phys.org/news/2023-05-prevalence-transposable-elements-clues-worldwide.html

Hi the fediverse!

Our lastest paper on the theoretical dynamics of transposable elements is out (in Theor Pop Biol: https://www.sciencedirect.com/science/article/pii/S0040580923000096 , in @biorxiv_evobio : https://www.biorxiv.org/content/10.1101/2022.07.05.498868v2). We derived population genetics models of TE amplification when regulated by piRNAs, accoding to the "trap model". -> Thread

#PopulationGenetics #TransposableElements #TheorPopBiol #piRNA #EvolutionaryBiology #EvoBio #Publication #Genomics

RT @Physacourses
🥁Registration is now open for the course "Bioinformatic analysis of Transposable Elements" with @valentina_peona & @clementgoubert in June

🗓️ (online) June, 12-15

🔗https://www.physalia-courses.org/courses-workshops/course24/

#TransposableElements #Genomics #Bioinformatics

And here is the new version of the manuscript !
Have fun reading it #nanopore #TransposableElements #snakemake #drosophila

https://www.biorxiv.org/content/10.1101/2022.07.21.500944v2

A #Postdoc position is available in our lab at @tu_muenchen on fungal #popgen in Blumeria species and #transposableelements. Knowledge and practical experience in bioinformatics and population genetics analysis of full genome data is desired. The salary is according to German/Bavarian income level TV-L E13 (100%). Informal inquiries can be addressed to me via email (aurelien.tellier@tum.de). Please RT. #EvolutionaryBiology #Genomics #Bioinformatics #Proteomics

#introduction
Hi! I am a Research Scientist at the Marine Biological Laboratory in Woods Hole. My research as molecular biologist lies at the junction of #molecular #evolution, #genomics and #epigenetics.
🧬 #transposableelements #TE #methylation

With our colleague Mourdas Mohamed from IGH, we juste released the new version of TrEMOLO for TE identification on long reads data! #transposableelements #bioinformatics #structuralvariations #genomics #software
Release v2.2-beta1 · DrosophilaGenomeEvolution/TrEMOLO https://github.com/DrosophilaGenomeEvolution/TrEMOLO/releases/tag/v2.2-beta

RT @jsantoyo
Transposable element finder (TEF): finding active transposable elements from next generation sequencing data. #TransposableElements #NGS @BMCBioinfo
https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-022-05011-3

RT @Julien_Pontis
Primate-specific transposable elements shape transcriptional networks during human development.
#TransposableElements #development #gastrulation #stemcells #enhancer #evolution #primates https://www.nature.com/articles/s41467-022-34800-w

#TransposableElements in #evolution . New paper from Hanne De Kort and others. Increased heterozygosity in #Arabidopsis lyrata is found near to TEs, and is hypothesised to play an important role in maintaining diversity despite inbreeding. Curiously the SNPs downstream of transposon start sites are enriched in genes with roles in stress resistance but not upstream. Interesting idea that this represents a selective advantage to maintaining TEs but, as authors acknowledge, might not be a direct relationship (i.e. TE spreading may result in increased mutation rate, which selection could then act on, even if TEs themselves are neutral or deleterious). Interesting to see if this is found in other species.
Link:

https://www.nature.com/articles/s41467-022-34795-4

Hi @alanhschulman !

Welcome to the other side! What kind of tools (both experimental and #bioinformatics) are key (or are you using) to construct the #pangenome?

Together with a student we are looking at a different kind of pangenomes - those of a family of #transposableElements. The main point is to study the group of sequences as a graph, instead of the more common multiple sequence #alignment.

#transposon

The #Fediscience #mastodon instance kindly asks for an #introduction. Here it is:

I am an evolutionary biologist at #IDEEV (#CNRS #UniversiteParisSaclay, France). Wide interests in #Evolution, including #PopGen, #QuantitativeGenetics, #SystemsBiology, and #Genome evolution (in particular, #TransposableElements). Mostly #Theory and #DataAnalysis.

I am part of the recent #twitterMigration of #Academia, and very happy to find so many people #ESEBFolks here!