Happy to report our review in Current Atherosclerosis Reports!
#Telomere Length: Implications for Atherogenesis
by me & my supervisor Dr. J. Geoffrey Pickering
TL as a biomarker & causal factor for ASCVD
Evidence from seminal studies, incld #UKBiobank #TOPMed
https://link.springer.com/article/10.1007/s11883-023-01082-6
AORTA score, a predictive model trained +common features (age/sex/BP...) in >30k #UKBiobank👤 explains 28-33% #AscendingAorticDiameter
Dr. James Pirruccello
Dr. Mark Lindsay @MarkELindsay Dr. Patrick Ellinor
JAMA 2022
https://jamanetwork.com/journals/jama/article-abstract/2798406
Enjoy the great🧵 by Dr. James Pirruccello
https://twitter.com/jpirruccello/status/1592596235751665666
#AscendingAorticDiameter #UKBiobank
Abdominal Aortic Calcification in #UKBiobank
38264👤
#MachineLearning to measure AAC
-Physio/Biochem predictors
-Cardiovascular outcomes
-Genetics TWIST1/HDAC9, FGF9, NAV1, APOE
Dr. Madeleine Cule & Eugene Melamud lab Frontiers Cardiovascular Medicine 2022
https://www.frontiersin.org/articles/10.3389/fcvm.2022.1003246/full