@biorxiv_genetics "Somatic cells of human males and females have 45 chromosomes in common, including the "active" X chromosome. In males the 46th chromosome is a Y; in females it is an "inactive" X (Xi). Through linear modeling of autosomal gene expression in cells from individuals with zero to three Xi and zero to four Y chromosomes, we found that Xi and Y impact autosomal expression broadly and with remarkably similar effects." #genetics #GeneExpression #XLinked #Xchromosome
#Xchromosome #xlinked #geneexpression #genetics
My newest research is published!
https://humgenomics.biomedcentral.com/articles/10.1186/s40246-023-00484-6
"The X-factor in ART: does the use of assisted reproductive technologies influence DNA methylation on the X chromosome?", Human Genomics, 2023
#dnamethylation #xchromosome #assistedreproductivetechnology #science #bioinformatics #epigenetics
#DNAmethylation #Xchromosome #assistedreproductivetechnology #science #bioinformatics #epigenetics
RT @Sadagopan_A@twitter.com
X-inactivation is prototypically female-specific. Today, we report somatic re-activation of the X-inactivation program in a subset of male cancers @CellSystemsCP@twitter.com
https://authors.elsevier.com/a/1g3838YyDfj7b1
@srviswanathan@twitter.com, C-Z Zhang, #Xchromosome #XIST
(1/9)
🐦🔗: https://twitter.com/Sadagopan_A/status/1590364552092606464
Silenced X chromosome genes reawaken in new mouse model
https://www.spectrumnews.org/news/toolbox/silenced-x-chromosome-genes-reawaken-in-new-mouse-model/
#Rettsyndrome #mousemodels #Xchromosome #treatments #Toolbox #autism #MECP2
#Rettsyndrome #mousemodels #Xchromosome #treatments #Toolbox #autism #MECP2
Trends in autism research 2021
https://www.spectrumnews.org/features/special-reports/trends-in-autism-research-2021/
#whole-genomesequencing #denovomutations #diagnostictests #SpecialReports #geneexpression #Xchromosome #aggression #sequencing #attention #community #diagnosis #mosaicism #autism #sex
#whole #denovomutations #diagnostictests #SpecialReports #geneexpression #Xchromosome #aggression #sequencing #attention #community #diagnosis #mosaicism #autism #sex
Huda Zoghbi: Taking genetic inquiry to the next level
https://www.spectrumnews.org/news/huda-zoghbi-taking-genetic-inquiry-to-the-next-level/
#learningandmemory #neuralcircuits #spokenversion #Rettsyndrome #motorskills #mousemodels #Xchromosome #treatments #Profiles #autism #memory #videos #MECP2 #News
#learningandmemory #neuralcircuits #spokenversion #Rettsyndrome #motorskills #mousemodels #Xchromosome #treatments #profiles #autism #memory #videos #MECP2 #news
Alternative gene-therapy approaches take aim at Rett syndrome
https://www.spectrumnews.org/news/alternative-gene-therapy-approaches-take-aim-at-rett-syndrome/
#spokenversion #Rettsyndrome #genetherapy #Xchromosome #mosaicism #autism #MECP2 #News
#spokenversion #Rettsyndrome #genetherapy #Xchromosome #mosaicism #autism #MECP2 #news