Data presented by @tajiknia #AACRJCA22 shows MRTX1133 suppression of pERK at nM doses & synergies with 5-FU in CRC & pancreatic cancer cells with #KRAS G12D, G12V, & G13D. More studies needed before excluding non-G12D mutations from trials @BrownUCancer @BrownMedicine #eldeirylab