Highly biased but interesting further pre clinical study suggesting epigenetic modulator (actually a circadian clock gene) is effective in animal models of #ALI #acutelunginjury has variable reasons why, it strongly upregulates anti oxidant defence genes via NRF-2, reinitiates protein synthesis&generates healthy fission fusion of mitochondria to the extent it’s used in sports doping - all cos cells compartmentalise what the do day/night #icm #criticalcare #medmastodon

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082412/

I've been telling my friends to take Vitamin D3. As is expected from my friends, they want some research to support my suggestion. Here's an open access article
"Vitamin D alleviates lipopolysaccharide‑induced acute lung injury via regulation of the renin‑angiotensin system" https://www.spandidos-publications.com/10.3892/mmr.2017.7546 #calcitriol #cholecalciferol #VitaminD #acutelunginjury