A team led by Georgia Tech’s Jeffrey Skolnick has developed #AF2Complex, a modified #AlphaFold algorithm, to understand how individual proteins form functional complexes within living cells. The strategy incorporates an interfacial similarity score to rate how well protein surfaces will stick together. They’ve used the strategy to study the cytochrome C pathway, important for energy production within cells and more. https://ascr-discovery.org/2023/01/computing-function-from-form/ #AI #proteinfolding #GeorgiaTech