Efficacy and Safety of #Anakinra Plus Standard of Care for Patients With Severe #COVID19 - A Randomized Phase 2/3 Clinical Trial, JAMA: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2803480?utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jamanetworkopen&utm_content=wklyforyou&utm_term=040723

#IDMastodon In this cohort study of 6,671 patients whose respiratory status deteriorated while receiving DEXA6 for COVID-19 pneumonia, and the findings do not support escalating patients with #COVID19 pneumonia who deteriorate on low-dose #corticosteroids to high-dose #dexamethasone or #anakinra.
https://www.sciencedirect.com/science/article/pii/S1201971222006038?dgcid=raven_sd_aip_email @ISDA

Une équipe discrète pour un travail intéressant contre le #Covid_19 : l'#anakinra.
On appréciera l'humilité de la conclusion:
"This report has limitations, such as the low number of patients and being a retrospective study"
https://www.pnas.org/content/117/32/18951