What is the role of #DNAdamage #kinase #DNAPKcs in the cellular response to #oxidative stress?
Benjamin Chen at UT Southwestern, Hsinyu Lee at National Taiwan University, and coworkers implicate it as part of a #checkpoint that modulates #ANT2-#VDAC2-mediated ADP-ATP exchange over #mitochondrial membranes to limit #OXPHOS-derived ROS
#dnadamage #Kinase #dnapkcs #oxidative #checkpoint #ant2 #vdac2 #mitochondrial #oxphos