NoTHiNg tO SeE hEre! ☀️🏖️
#DirtyAir: Worsening #airpollution and increased #resistance to #antibiotics are two of the world’s most urgent #publichealth concerns, contributing to millions of #prematuredeaths per year
#AcceleratingKeelingCurve #DegradingTheCommons #TragedyOfEnclosure
https://www.washingtonpost.com/health/2023/08/09/air-pollution-antibiotic-resistance-link
#dirtyair #airpollution #resistance #antibiotics #publichealth #prematuredeaths #acceleratingkeelingcurve #degradingthecommons #tragedyofenclosure
@medrxivpreprint
The commonly used #antibiotics #amoxicillin, #metronidazole, #piperacillin-tazobactam & #Clindamycin reached levels equivalent to blood within infected pleural fluid.Low penetration of trimethoprim into the pleural space raised concerns about the use of #cotrimoxazole for patients with #Pleuralinfection or parapneumonic effusions.
#Antibiotic #pharmacokinetics in infected #pleuraleffusions
https://www.medrxiv.org/content/10.1101/2023.09.08.23295282v1.full.pdf
#antibiotics #Amoxicillin #metronidazole #piperacillin #clindamycin #cotrimoxazole #pleuralinfection #antibiotic #pharmacokinetics #pleuraleffusions
Langt på landet..
(69.579 km 🚴 since my ❤️-attack in 2016).
#stravacycling
#giantcontend #giant
#sweetprotection
#wahoo
#metoprolol #diabetes #gout #antibiotics
https://www.instagram.com/p/Cw-MyOuMU0z/?igshid=MTc4MmM1YmI2Ng==
#stravacycling #giantcontend #giant #sweetprotection #wahoo #metoprolol #diabetes #gout #antibiotics
Linezolid probably a bit safer than we think & probably can give >4 weeks with close observation.
Great drug, it's oral, but still makes me a bit apprehensive about using it for a long course, certainly at 600mg BD.
#IDMastodon #MedMastodon #AMR #antibiotics #microbiology #medicine #linezolid
Prolonged use of linezolid in bone and joint infections: a retrospective analysis of adverse effects | Journal of Antimicrobial Chemotherapy | Oxford Academic https://academic.oup.com/jac/advance-article/doi/10.1093/jac/dkad276/7264092
#IDMastodon #MedMastodon #AMR #antibiotics #microbiology #medicine #linezolid
Reminder to pick your outcomes.
Vancomycin vs Fidaxomicin in #Cdiff- same mortality, but lower recurrence with fidaxo
#Clostridiumdifficile #antibiotics #microbiology #IDMastodon #infectiousdeseases
The Effect of Antibiotic Therapy for Clostridioides difficile Infection on Mortality and Other Patient-Relevant Outcomes: a Systematic Review and Meta-analysis - Clinical Microbiology and Infection https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(23)00420-2/fulltext
#Cdiff #clostridiumdifficile #antibiotics #microbiology #IDMastodon #infectiousdeseases
Was ist eigentlich mit MRSA (Methicillin-resistant Staphylococcus aureus - ein Bacterium das multiresistent gegen viele Antibiotika ist)? Und wie sieht es bzgl. Neu- und Weiterentwicklung von Antibiotika aus?
#mrsa #antibiotics #bacteria #cdc #healthcare
#BBCNews - #Kumbh #Mela : Worry at #antibiotics overuse at #India 's #KumbhMela
https://www.bbc.co.uk/news/world-asia-india-66656851
#bbcnews #kumbh #mela #antibiotics #India #kumbhmela
https://www.forbes.com/sites/judystone/2015/11/09/common-antibiotics-cause-arrhythmias-death-and-everything-else/?sh=6bdb60cdd170 Common Antibiotics Cause Arrhythmias, Death And Everything Else #vaccines #antibiotics #arrhythmias #death
#vaccines #antibiotics #arrhythmias #death
We may be losing #cefiderocol far sooner than we hoped.
Timely meta-analysis. Look at those #resistance rates in #carbapenem resistant Enterobacterales!
#microbiology #AMR #antibiotics #antibiotic #CriticalCare #Pseudomonas #Acenitobacter #infectiousdiseases #IDMastodon #medicine
#cefiderocol #resistance #carbapenem #microbiology #AMR #antibiotics #antibiotic #CriticalCare #Pseudomonas #acenitobacter #infectiousdiseases #IDMastodon #medicine
By extensively using mutations, researchers tested a full range of variants of antibiotics to find the ones that are most effective in attacking some bacteria. This way new antibiotics may be developed to treat infections that are resistant to existing antibiotics. See http://www.neat-news.com/2023/09/244.php. #antibiotics #resistance
I find direct consumer access to #antibiotics rather 😱 - very little #stewardship
#AMR #microbiology #infectiousdiseases #medicine #IDMastodon
https://academic.oup.com/cid/advance-article-abstract/doi/10.1093/cid/ciad472/7252952
#antibiotics #AMR #microbiology #infectiousdiseases #medicine #IDMastodon #stewardship
This is intriguing: phage therapy induces bacterial resistance but also reduced virulence.
So clinical benefit post-phage could also stem from bacterial attenuation rather than just eradication.
Question is how sustainable this effect may be.
#Phages #bacteria #microbiology #IDMastodon #medicine #MedMastodon #AMR #antibiotics #bacteriophage
https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(23)00405-6/fulltext?dgcid=raven_jbs_aip_email
#phages #bacteria #microbiology #IDMastodon #medicine #MedMastodon #AMR #antibiotics #bacteriophage
#Food - Do #antibiotics really wipe out your gut bacteria?
https://www.bbc.com/future/article/20230825-do-antibiotics-really-wipe-out-your-gut-bacteria
ESCMID guidelines on diagnosis and treatment of brain abscess in children and adults - Clinical Microbiology and Infection
#IDMastodon #MedMastodon #AMR #antibiotics #microbiology #antimicrobialstewardship #infectiousdiseases #medicine @infectiousdiseases @microbiology #brain #abscess
#IDMastodon #MedMastodon #AMR #antibiotics #microbiology #antimicrobialstewardship #infectiousdiseases #medicine #brain #abscess
Great talk by Kevin Neumann at #IUPACCHAINS2023. He talked about his group's work on zitterionic polymers as coatings to prevent bacterial biofilms. Exciting chemistry of stable ylides to have a minimal distance between positive and negative charge. #Chemistry #ChemiVerse #Polymers #Antibiotics https://doi.org/10.1002/anie.202308971
#iupacchains2023 #chemistry #chemiverse #polymers #antibiotics
Interesting talk by Marko Radojković from the Leiden Insitute of Chemistry in the "Antibiotics and Antivirals" session of #IUPACCHAINS2023. He talked about his research on better understanding enzyme evolution on the example of the β-lactamase BlaC.
#Chemistry #ChemiVerse #Antibiotics
#iupacchains2023 #chemistry #chemiverse #antibiotics
Reminder that unnecessary use of #antibiotics can actively promote / select for #resistance #AMR
#IDMastodon #microbiology #microbiome #medicine #infectiousdiseases @microbiology @infectiousdiseases
#antibiotics #resistance #AMR #IDMastodon #microbiology #microbiome #medicine #infectiousdiseases
"On Tuesday, an international team announced in the journal Cell that they had identified a potential new antibiotic lurking unnoticed in the sandy soil of North Carolina. The compound, called clovibactin, employs an unusual method of killing bacteria that makes it tough for targets to develop resistance. While clinical trials in humans are several years away, the finding is a glimmer of hope in an increasingly drug-resistant world."
#microbiology #antibioticresistance #antibiotics #drugdevelopment
https://www.ft.com/content/a8d62524-3f3f-4d61-a27f-a689a13f9232
#antibioticresistance #microbiology #antibiotics #drugdevelopment
An antibiotic from an uncultured bacterium binds to an immutable target | Cell
New antibiotic dropped.
"we report the discovery of clovibactin.... efficiently kills drug-resistant Gram-positive bacterial pathogens without detectable resistance" #microbiology #antibiotics
Katherine Duncan from Strathclyde University:
Linking genes and metabolites for informed antibiotic discovery
#jgi2023 #actinomycetes #streptomyces #antibiotics #JGI