RT @TimothyPJenkins: Unlocking Opportunities: InstaNovo holds the potential for numerous applications. From sequencing #antibody-based therapeutics with unprecedented coverage to uncovering novel #cancer peptides, and exploring the #darkproteome, this broadens the scope of proteomics searches.
#antibody #cancer #darkproteome
🚨10 selected #researchluxembourg results 🚨
✅ An effective #antibody against #skincancer🧪
✅ How youth perceive their #weight🪞
✅ The fabulous destiny of #polaritons🔬
✅ European #healthdata⚕️
✅ The #overconsumption of harmful products📈
✅ The #housingmarket in #Luxembourg🏠
Discover the other #science & #research news from Luxembourg in July 2023 ➡️ https://www.researchluxembourg.org/en/10-selected-research-luxembourg-results-july-2023/
#research #science #luxembourg #housingmarket #overconsumption #healthdata #polaritons #weight #skincancer #antibody #researchluxembourg
Global #COVID monitoring is crashing as BA.2.86 #COVIDvariant raises alarm
The number of mutations in #BA2.86's critical #spikeprotein is over 30, rivaling the number seen in the original omicron subvariant, #BA1, which went on to cause a tidal wave of cases and hospitalizations. The spike mutations appear geared toward evading neutralizing #antibody protections built up from past infections and #vaccinations.
"This is on the shoulders of governments right now." https://arstechnica.com/health/2023/08/global-covid-monitoring-is-crashing-as-ba-2-86-variant-raises-alarm/
#covid #covidvariant #ba2 #spikeprotein #ba1 #antibody #vaccinations
Comparison of Clinical Manifestations of #kawasakidisease According to #SarsCoV2 #Antibody Positivity in children .the clinical manifestations of KD between patients with and without severe #SARSCoV2 antibodies. And Abnormal post-infectious immunological reactions may play a key role in pathogenesis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279516/
https://repository.brieflands.com/items/f80621d8-4355-48ed-8482-0ae8466afadb/full
#kawasakidisease #SarsCoV2 #antibody
The emergence of new #antigen #branches of #H9N2 avian #influenza virus in #China due to antigenic drift on #hemagglutinin through #antibody escape at immunodominant sites, Emerg Microbes Infect., https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2246582 #science #research #zoonoses #panzootic #epizootic #enzootic #pandemic
#antigen #branches #H9N2 #influenza #china #hemagglutinin #antibody #Science #research #Zoonoses #panzootic #epizootic #enzootic #pandemic
#idw Three doses of #Covid-19 #vaccine leads to catch-up #antibody responses among the particularly vulnerable.
Even vulnerable people, who are at risk of severe Covid-19, achieved good antibody levels after three doses of #mRNA vaccine. This is shown by a study from the University of Gothenburg on patients having undergone a bone marrow transplant or with liver disease, including cirrhosis. https://idw-online.de/en/news818842
Link Englisch: https://idw-online.de/en/news818842
#idw #covid #vaccine #antibody #mrna
Elevated #binding and functional #antibody responses to #SARS-CoV-2 in #infants versus #mothers, Nat Commun.: https://www.nature.com/articles/s41467-023-40554-w #immunity #immunology #pregnancy #pediatrics #medicine #research
#Binding #antibody #sars #infants #mothers #immunity #immunology #pregnancy #pediatrics #medicine #research
Post-Doc: Antibody engineering
CEA, France
Join us in the construction of next generation bi-(multi-) specific antibodies.
#quantitative two-hybrid
#Antibody engineering
#Post-Doc
See the full job description on jobRxiv: https://jobrxiv.org/job/cea-france-27778-post-doc-antibody-engineering/?feed_id=54357
#ScienceJobs #hiring #research #CEA, #antibody engineering, #SIMoS, #Molecular evolution, #Synthet...
https://jobrxiv.org/job/cea-france-27778-post-doc-antibody-engineering/?feed_id=54357
#synthet #molecular #simos #cea #research #hiring #ScienceJobs #post #antibody #quantitative
A clinical trial assessing a synthetic antibody to generate an immediate response and also generate a more durable treatment for solid tumor cancers, advanced to a mid-stage study.
https://sciencebusiness.technewslit.com/?p=45068
#News #Press #Science #Business #Cancer #Biotechnology #ClinicalTrial #Immunotherapy #AdverseEffects #CheckpointInhibitor #Antibody #ImmuneSystem #TCells #InnateImmuneSystem
#News #press #science #business #cancer #biotechnology #ClinicalTrial #Immunotherapy #adverseeffects #checkpointinhibitor #antibody #immunesystem #Tcells #innateimmunesystem
#IDMastodon #Drugdiscovery #Drugdevelopment @DDWJournal #Antibody discovery: Breakthroughs accelerating therapeutic antibodies .Trend and Challenge for therapeutic antibody in pandemic era
https://7915828.fs1.hubspotusercontent-na1.net/hubfs/7915828/DDW%20eBOOK%20ANTIBODY%20DISCOVERY_PROTECTED_FINAL.pdf?hsCtaTracking=b9795c08-6d89-4543-97ad-90cc3c6eae68%7C7aadb240-d29f-4505-a29e-578edfcc66da
#IDMastodon #DrugDiscovery #DrugDevelopment #antibody
#IDMastodon #pedslD The #SARSCoV2 #mRNAvaccines (BNT162b2) & (mRNA-1273) are approved by EMEA & @fda_drug_info for use in children from 6 mths of age. These vaccines offer excellent protection from severe disease & #Longcovid in children & adults that also protect children from MIS-C .At a comparable dose (100 μg), children aged 6–11 years elicit higher titre #antibody responses to the mRNA-1273 vaccine vs adults and with stronger Fc binding capacity.
#IDMastodon #pedsld #SarsCoV2 #mrnavaccines #LongCovid #antibody
More evidence for AAV-2 as cause for severe acute hepatitis of unknown etiology in children
#Science #hepatitis #medicine #MedMastodon #virology #antibody #serology
https://www.science.org/doi/10.1126/scitranslmed.adh9917
> AAV-2–reactive antibodies and evidence of AAV-2 helper virus infection are associated with pediatric severe acute hepatitis of unknown etiology.
#Science #hepatitis #medicine #MedMastodon #virology #antibody #Serology
Post-Doc: Antibody engineering
CEA, France
Join us in the construction of next generation bi-(multi-) specific antibodies.
#quantitative two-hybrid
#Antibody engineering
#Post-Doc
See the full job description on jobRxiv: https://jobrxiv.org/job/cea-france-27778-post-doc-antibody-engineering/?feed_id=51927
#ScienceJobs #hiring #research #CEA, #antibody engineering, #SIMoS, #Molecular evolution, #Synthet...
https://jobrxiv.org/job/cea-france-27778-post-doc-antibody-engineering/?feed_id=51927
#synthet #molecular #simos #cea #research #hiring #ScienceJobs #post #antibody #quantitative
Eli Lilly #drug shown to slow #Alzheimer’s progression
#Dementia experts hail "watershed moment" after trial results for #donanemab #antibody treatment showed it slowed progression by about 35% in the early stages of the disease. https://arstechnica.com/health/2023/07/eli-lilly-drug-shown-to-slow-alzheimers-progression/
#drug #alzheimer #dementia #donanemab #antibody
“We further demonstrated #transcriptional changes in infected syncytiotrophoblasts that led to impairment of #cellular processes, reduced secretion of #HCG hormone and morphological changes vital for syncytiotrophoblast function. Furthermore, different #antibody strategies and #antiviral drugs restore these impairments.”
#transcriptional #cellular #hcg #antibody #Antiviral
Additive effects of booster mRNA vaccination and SARS-CoV-2 Omicron infection on T cell immunity across immunocompromised states | Science Translational Medicine https://www.science.org/doi/10.1126/scitranslmed.adg9452 “#Omicron-reactive #Tcell responses that increased markedly upon #booster #vaccination and correlated directly with #antibody #titers across all patient groups. Poor vaccination responsiveness in #immunocompromised or #elderly individuals was effectively counteracted by the administration of additional doses.”
#omicron #TCell #booster #vaccination #antibody #titers #immunocompromised #elderly
#IDMastodon #Immunology #COVID19 / #SARSCoV2 mRNA vaccination induces a robust systemic & intranasal #antibody production with neutralizing capacity. Spikevax™ (Moderna) vaccinations elicits a greater antibody response compared to Comirnaty® (BioNTech/Pfizer) vaccination systemically & intranasally.
📌 https://www.jaci-global.org/article/S2772-8293(23)00054-1/pdf
📌 https://pink.pharmaintelligence.informa.com/PS146361/EMA-Assessing-VariantAdapted-Spikevax-Probes-Heart-Inflammation-With-Nuvaxovid
#IDMastodon #immunology #COVID19 #SarsCoV2 #antibody
Bivalent #COVID-19 #vaccine #antibody responses to #Omicron #variants suggest that responses to #divergent variants would be improved with matched vaccine antigens https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiad111/7190664?rss=1
#covid #vaccine #antibody #omicron #variants #divergent
#Antibody #signatures in hospitalized #HFMD #patients with acute #EV-A71 infection https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1011420
#antibody #signatures #hfmd #patients #ev
Long term anti- #SARS-CoV-2 #antibody #kinetics and correlate of #protection against #Omicron BA.1/ #BA2 infection https://www.nature.com/articles/s41467-023-38744-7
#sars #antibody #kinetics #protection #omicron #ba2