Another hot-off-the-press preprint on #Drosophila host - #microbiome interactions:

Lactobacillus plantarum is resistant to host #antimicrobialpeptides (AMPs) thanks to characteristics of its peptidoglycan that make its cell wall less sensitive to AMPs than other #bacteria. 🦠

Definitely adding to my reading list! Congrats to Aranzazu et al. and Igor Iatsenko, whose new lab has been knocking it out of the park! ⚾

https://www.biorxiv.org/content/10.1101/2023.03.21.533593v1

Referenced link: https://phys.org/news/2023-02-ai-based-finder-antimicrobial-peptides.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-02-ai-based-finder-antimicrobial-peptides.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1628776964214472710#m

Researchers develop a new AI-based 'finder' of #antimicrobialpeptides https://onlinelibrary.wiley.com/doi/10.1002/pro.4529 https://phys.org/news/2023-02-ai-based-finder-antimicrobial-peptides.html

🦠 I'm happy to present a new nf-core pipeline for people interested in functional analysis of #MicrobialGenomes / #Metagenomes / #Microbiomes !

If you're interested in mining metagenomes for functional groups such as #AntiMicrobialResistance genes, #AntiMicrobialPeptides or #BiosyntheticGeneClusters, @nf_core /funcscan automates the screening of such sequences from input contigs or genomes in a highly parallelised, portable, and reproducible manner

https://genomic.social/@nf_core@mstdn.science/109868600236675816 🧵 [1/2]

RT @HansonM90@twitter.com

This pub culminates my last 10 years🎉
We find that #antimicrobialpeptides are evolved to control specific #microbiome bacteria. This example is a textbook case of host #immune #evolution being shaped by the microbiome 🦠, which depends on host #ecology

https://biorxiv.org/content/10.1101/2022.12.23.521774v2.full

🐦🔗: https://twitter.com/HansonM90/status/1610560026506104833

RT @HansonM90
This pub culminates my last 10 years🎉
We find that #antimicrobialpeptides are evolved to control specific #microbiome bacteria. This example is a textbook case of host #immune #evolution being shaped by the microbiome 🦠, which depends on host #ecology

https://biorxiv.org/content/10.1101/2022.12.23.521774v2.full

This pub culminates my last 10 years🎉
We find that #antimicrobialpeptides are evolved to control specific #microbiome bacteria. This example is a textbook case of host #immune #evolution being shaped by the microbiome 🦠, which depends on host #ecology

https://biorxiv.org/content/10.1101/2022.12.23.521774v2.full

Happy to announce this pub, which is the culmination of last 10 years of my career beginning as far back as my MSc🎓
We find that #antimicrobialpeptides are evolved to control specific #microbiome bacteria. This example is a textbook case of host #immune #evolution being shaped by the microbiome 🦠

https://www.biorxiv.org/content/10.1101/2022.12.23.521774v2.full

"On taking a blood meal, mosquitoes with the modification produce two antimicrobial peptides (AMPs) in the gut, which impair the malaria parasite’s development. The two peptides are magainin 2, which was first found within skin secretions of the African claw frog Xenopus laevis, and melittin, a primary toxin component of the European honey bee Apis mellifera." #malaria, #antimicrobialpeptides #genedrive

https://www.genengnews.com/topics/translational-medicine/infectious-diseases/genetically-modified-mosquitoes-stunt-malaria-parasite-growth-prevent-transmission/?MailingID=%DEPLOYMENTID%&utm_medium=newsletter&utm_source=GEN+Daily+News+Highlights&utm_content=01&utm_campaign=GEN+Daily+News+Highlights_20221226&oly_enc_id=6688E2244356C6Z

Referenced link: https://phys.org/news/2022-11-lab-pathway-antimicrobial-peptides.html
Discuss on https://discu.eu/q/https://phys.org/news/2022-11-lab-pathway-antimicrobial-peptides.html

Originally posted by Phys.org / @physorg_com@twitter.com: https://twitter.com/physorg_com/status/1592190383752380416#m

#Lab discovers new pathway for #antimicrobialpeptides @princeton @J_A_C_S @NatureChemistry https://www.nature.com/articles/s41557-022-01063-3 https://phys.org/news/2022-11-lab-pathway-antimicrobial-peptides.html

Hi all, I work on #immunity specifically #evolution and #antimicrobialpeptides or "AMPs." I've used #Drosophila as a model, but also like to keep other species in mind about universality of principles.

Cheers! Toot toot 🐘

Google scholar: https://scholar.google.ca/citations?user=lfL-37cAAAAJ&hl=en