Dor Salomon · @DrDorSalomon
44 followers · 11 posts · Server genomic.social

New preprint from our lab. We report that genomic islands containing Gamma-Mobile-Trio proteins are bacterial armories stockpiled with antibacterial, anti-phage, and anti-eukaryotic weapons.
This one has something for everybody:
biorxiv.org/content/10.1101/20

#antiphage #t6ss #Vibrio #MGE

Last updated 1 year ago

Vivek Mutalik · @vivek_mutalik
673 followers · 899 posts · Server fediscience.org

An E1–E2 fusion protein primes immune signalling in bacteria | Nature

nature.com/articles/s41586-022

#antiphage #phage #antiviral

Last updated 1 year ago

Vivek Mutalik · @vivek_mutalik
649 followers · 770 posts · Server fediscience.org
Vivek Mutalik · @vivek_mutalik
636 followers · 679 posts · Server fediscience.org

A conserved family of immune effectors cleaves cellular ATP upon infection |

biorxiv.org/content/10.1101/20

#antiphage #phage #viral

Last updated 2 years ago

Vivek Mutalik · @vivek_mutalik
628 followers · 625 posts · Server fediscience.org

Synergy and regulation of systems: toward the existence of a bacterial immune system? -

sciencedirect.com/science/arti

#Phages #phage #antiphage

Last updated 2 years ago

Vivek Mutalik · @vivek_mutalik
556 followers · 444 posts · Server fediscience.org
Vivek Mutalik · @vivek_mutalik
463 followers · 330 posts · Server fediscience.org
Sarah Melamed · @Curiousphage
56 followers · 18 posts · Server fediscience.org

Antiviral signaling by a cyclic nucleotide activated CRISPR protease
nature.com/articles/s41586-022

#crispr #antiphage #immunesystem #bacteria #phage

Last updated 2 years ago

Vivek Mutalik · @vivek_mutalik
366 followers · 167 posts · Server fediscience.org

Antiviral signaling by a cyclic nucleotide activated protease

nature.com/articles/s41586-022

#phage #signaling #antiphage #crispr

Last updated 2 years ago

Aude Bernheim · @audeber
193 followers · 6 posts · Server mstdn.science

Our initial census of systems in genomes revealed that on average bacteria encode at least 6 anti-phage mechanisms. This paves the way for many interactions between systems.

So we decided to review the existing litterature about and of systems.

Already cool stuff and clearly a lot more to discover :). Hopefully, this can help to think about how multiple systems coexist in a cell !

sciencedirect.com/science/arti

#antiphage #synergy #regulation

Last updated 2 years ago