#Glucagon #receptor structures uncover new #arrestin interaction mechanism.
#signalling #transduction #GPCR
https://phys.org/news/2023-08-glucagon-receptor-uncover-arrestin-interaction.html
#glucagon #receptor #arrestin #signalling #transduction #gpcr
A major #hydrogenbond network within #Angiotensin II #receptor 1 determines signaling towards #Gq #Gprotein or beta-#arrestin in response to balanced or biased receptor agonists
#CryoEM structural and functional data by Haitao Zhang and coworkers with implications for #pharmacological targeting to control #bloodpressure and confer heart protection
https://www.embopress.org
/doi/10.15252/embj.2022112940
#hydrogenbond #angiotensin #receptor #gq #gprotein #arrestin #cryoem #pharmacological #BloodPressure