“lingering symptoms” is not how I've heard a single person with #LongCovid describe it..
#Disability #ViralPersistence #OrganDamage #Autoimmunity #ShortenedLifeExpectancy
#LongCOVID #disability #viralpersistence #OrganDamage #autoimmunity #shortenedlifeexpectancy
Had a wild shower thought today. I am not an immunologist and I bet I am not the first to have the thought, and maybe it’s naïve, but.
What if my immune system is attacking my skin and joints because that is where the virus that started all of this is hiding?
Surely, we have tried treating psoriatic and rheumatoid arthritis with strong antivirals, right? Right? #immunology #autoimmunity #ChronicIllness #spoonie #IVolunteerAsTribute #TestItOnMe
#immunology #autoimmunity #chronicillness #spoonie #ivolunteerastribute #testitonme
Fresh from the press 📰! Spearheaded by Isabel from H. Prüss' group, our article explores synapsing autoantibodies and their link to fetal abnormalities. We found a 13.3% prevalence of anti-syn in pregnant women, which was associated with neurodevelopmental disorders. Check out Figure 3, where we reveal patient-specific epitopes. 🧠🔬 #autoimmunity #peptides #synapses
#autoimmunity #peptides #synapses
#IDMastodon #microbiology #BraingutAxis #Neuroimmunology lactate-induced HIF1α activation in the context of CNS #autoimmunity initiates a regulatory loop in DCs that limits #immunopathology.
#IDMastodon #microbiology #braingutaxis #neuroimmunology #autoimmunity #immunopathology
#IDMastodon #BraingutAxis #Neuroimmunology @naturemedicine
lactate-induced HIF1α activation in the context of CNS #autoimmunity initiates a regulatory loop in DCs that limits #immunopathology.
#IDMastodon #braingutaxis #neuroimmunology #autoimmunity #immunopathology
Celiac gene carriers may want to avoid since it contains microbial transglutaminase:
https://doi.org/10.12998%2Fwjcc.v7.i22.3912
#celiac #foodadditives #autoimmunity
Promising but early (phase 2) data on a second generation of anti CD40L monoclonals for #multiplesclerosis
My latest #ClinicalPipeline column for Nature Medicine.
#Immunology #autoimmunedisease #Autoimmunity
#multiplesclerosis #ClinicalPipeline #immunology #autoimmunedisease #autoimmunity
'Zhang et al. provide crucial insights into the mechanisms driving the transition from the onset of autoimmunity to joint destruction in rheumatoid arthritis. The findings emphasize the central role of myeloid monocytes that overexpress both RANK and TLR2, and the sialylation of TLR2 in driving the fusion of monocytes and consequent resorption of bone.'
#immunology #autoimmunity #rheumatoidarthritis
@halama_immuno
Wow, that's high!
Though slightly confounded by increased life expectancy, but still!
#immunology #autoimmunity #autoimmunedisease #epidemiology
#immunology #autoimmunity #autoimmunedisease #epidemiology
Incidence and prevalence of 19 autoimmune diseases in the UK estimates that 1:10 individuals will suffer from at least one.
#Immunology #Autoimmunity #AutoimmuneDisease #Epidemiology
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)00457-9/fulltext
#immunology #autoimmunity #autoimmunedisease #epidemiology
⚠️ WATCH THIS ⚠️
Prof. Simon, sports medicine at the @uni_mainz give a lecture on
(0:47 min - 1h 18)
👇🏻👇🏻👇🏻
#PEM
#EndothelialDysfuntion
#Autoimmunity
#LactateMetabolism
for #LongCovid/#MECFS
and the „30s-rule“ to avoid muscular malaise
1/2
👉 vimeo.com/771944349
#pem #endothelialdysfuntion #autoimmunity #lactatemetabolism #LongCovid
A cardinal feature of the #immune system is its ability to distinguish self from nonself. Sometimes, however, this delicate balancing act fails.
This special issue of Science highlights recent advances in our understanding of #autoimmunity. https://scim.ag/2tV #press
"... active and heavy tobacco smoking ... is the most important environmental risk factor for [rheumatoid arthritis] with its attributable risk sustained for up to 20 years after discontinuation ..."
https://doi.org/10.1186/s12950-015-0092-1
#RheumatoidArthritis #autoimmunity #AutoimmuneDisease #health
#rheumatoidarthritis #autoimmunity #autoimmunedisease #health
New publication of so-called #TeamClots with #ResiaPretorius on the pathophysiology of #LongCovid. The focus is on #Microclots.
But also other theories like #Autoimmunity and #ViralPersistence are mentioned.
#PostCovid #MECFS #Covid #Corona #Covid19 #Science
https://www.sciencedirect.com/science/article/pii/S1043276023000553
#science #COVID19 #corona #covid #mecfs #PostCovid #viralpersistence #autoimmunity #microclots #LongCovid #resiapretorius #TeamClots
When the immune system attacks the immune system: #Autoantibodies against #interferons (type I) have an impact on #immuneresponses and are associated with viral disease susceptibility as outlined in this elegant review... #immunology #virology #cytokines #infections #autoimmunity #immunoregulation
https://onlinelibrary.wiley.com/doi/abs/10.1002/eji.202250164
#autoantibodies #interferons #immuneresponses #immunology #virology #cytokines #infections #autoimmunity #immunoregulation
Also in @sciencemagazine this week: Giuseppe Matarese pens a Perspective on the link between #obesity and #autoimmunity!
#immunometabolism #overnutrition #T1D #MS #Tregs #adipocytes #CaloricRestriction #immunotherapy
#immunotherapy #caloricrestriction #adipocytes #tregs #ms #t1d #overnutrition #immunometabolism #autoimmunity #Obesity
Possible Trigger For Celiac Disease: Best Of: 2018
A common food additive may cause autoimmune celiac disease. Microbial transglutaminase used to glue food together may be the culprit.
#celiac #transglutaminase #autoimmunity #mTG #foodadditive
https://youtu.be/LiuC2g-tfcA
#celiac #transglutaminase #autoimmunity #mtg #foodadditive
Bonus #TWiVTLDR fact, from the longer SUPER science-y episode they had about the polio shedder cured with remdesivir: https://www.microbe.tv/twiv/twiv-993/
#Autoimmunity problems happen if you get #COVID, but NOT when you get any of the mRNA #vaccines.
#twivtldr #autoimmunity #COVID #vaccines
#cardiomastodon #IDMatodon Sugar, salt, #immunity and the cause of primary hypertension . Role of Subtle Renal Injury and #autoimmunity ,#Hyperuricemia & the Initiation of #Hypertension .
📌 https://academic.oup.com/ckj/advance-article/doi/10.1093/ckj/sfad058/7085008?login=false
📌 https://academic.oup.com/ckj
📌 https://www.researchgate.net/publication/332654820_The_Influence_of_Dietary_Salt_Beyond_Blood_Pressure
📌 https://www.researchgate.net/journal/Current-Hypertension-Reports-1534-3111
#cardiomastodon #idmatodon #immunity #autoimmunity #hyperuricemia #hypertension