CellBioNews · @cellbionews
45 followers · 983 posts · Server scientificnetwork.deResearchers reveal crucial role of #RNA in modulating #autophagic degradation of #protein condensates.
https://phys.org/news/2023-04-reveal-crucial-role-rna-modulating.html
#RNA #autophagic #protein #pgl #sepa #eif4e
The EMBO Journal · @embojournal
426 followers · 141 posts · Server sciencemastodon.com
TFEB-dependent lysosome biogenesis is required for #senescence
by Bernadette Carroll and coworkers
Transcription factor #TFEB induces #lysosome proliferation in #senescent cells, counterbalancing reduced lysosomal efficiency and maintaining #autophagic capacity
https://www.embopress.org/doi/10.15252/embj.2022111241
#senescence #tfeb #lysosome #senescent #autophagic
The EMBO Journal · @embojournal
426 followers · 140 posts · Server sciencemastodon.com
A #protelysis cascade fine-tunes homologous #recombination repair in plants:
Arp Schnittger and coworkers show #KNOTEN1, stabilized by #UBP12/13, triggering K63-linked #ubiquitination and #autophagic degradation of #BLM complex subunit #RMI1 upon #DNAdamage
#protelysis #Recombination #knoten1 #ubp12 #ubiquitination #autophagic #BLM #rmi1 #dnadamage
Knight ADRC · @KnightADRC
21 followers · 155 posts · Server universeodon.com
RT @B_A_Benitez@twitter.com
Molecular networks associated with #lysosomal biogenesis, #autophagic function & #proteastasis are disrupted in brains, #iPSC (#CRISPR) & #organoids from FTLD-tau patients (MAPT p.R406W mutation) by Dr. Sid Mahali in @karchlab@twitter.com @WUSTLmed@twitter.com via @Transl_Psych@twitter.com https://www.nature.com/articles/s41398-022-02274-5
🐦🔗: https://twitter.com/B_A_Benitez/status/1601574411403829248
#lysosomal #autophagic #proteastasis #ipsc #crispr #organoids