TOR-mediated Ypt1 #phosphorylation regulates autophagy initiation complex assembly

The Rab #GTPase #Ypt1 serves as a bridge that connects environmental sensing to the formation of the #autophagy initiation complex.

https://www.embopress.org/doi/full/10.15252/embj.2022112814

https://autophagy.science/autophagy-supplements/ Autophagy regenerates every cell in your body, particularly damaged DNA cells (like those created by the covid-19 mRNA vaccines.) Autophagy is a natural process that happens when you fast (without protein consumption so it can rid your body of damaged protein chains (spike proteins) and rebuild healthy new cells. If you need healing ASAP then you will want to use Autophagy Activators that make the process happen faster and deeper. Repair your DNA and get full body cellular regeneration and deep healing on all levels. It works well during prolonged or intermittent fasting. Use it if you’re on a healthy ketogenic diet to enhance your healing and weight loss results dramatically. #autophagy #dna #regeneration #mRNA #healing

Number of #DNA copies influences the #cell #death process that shapes organs during #embryonic development: Study.

#autophagy #polyploidy

https://phys.org/news/2023-07-dna-cell-death-embryonic.html

Issue 14:
Highlight on #ROR1 and #pancreatic #malignancy

Review on viral recognition and #antiviral #interferon response

#Autophagy news from plants and mammals
How #p97 disassembles a regulatory protein complex
Developmental #axon pruning by a #phospholipid #scramblase

Cover: Elisa Nerli, Caren Norden and colleagues

https://www.embopress.org/toc/14602075/2023/42/14

➡️ Generative AI Goes 'MAD' When Trained on AI-Created Data Over Five Times https://www.tomshardware.com/news/generative-ai-goes-mad-when-trained-on-artificial-data-over-five-times

Relacionado:
➡️ The Curse of Recursion: Training on Generated Data Makes Models Forget https://arxiv.org/abs/2305.17493 (via https://masto.ai/@zoomar/110548591762067907)

Se puede detectar si algo está generado por «inteligencia» artificial. Para el ser humano puede ser imperceptible pero no para la estadística. Y la prueba está en que si entrenas un modelo con sus propias salidas acaba generando una «señal» periódica mucho más evidente. Es un poco como el tapón clonador de GIMP/Photoshop. Si utilizas la brocha gorda se nota mucho las áreas de imagen clonadas ya que utilizas pocas muestras de imagen. Si utilizas brocha fina pillas más muestras de imagen, hay más aleatoriedad (entropía) y el resultado es que no se nota tanto. Ahora bien, aún con brocha fina si las muestras no paras de cogerlas del mismo área la entropía se reduce y al final acabas repitiendo lo mismo una y otra vez.
➡️ Entropía (información) https://es.wikipedia.org/wiki/Entrop%C3%ADa_(informaci%C3%B3n)

#MAD #Generative #AI #IA #inteligenciaartificial #artificialintelligence #ModelAutophagyDisorder #Autophagy

Postdoctoral Researcher

Icahn School of Medicine at Mount Sinai (ISMMS)

Come join us in the #LazarusLab as bio postdoc at #MountSinai #Autophagy #ChemicalBiology #NYC

See the full job description on jobRxiv: https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai-ismms-27778-postdoctoral-researcher-2/?feed_id=49076

#ScienceJobs #hiring #research
New York City #Un...
https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai-ismms-27778-postdoctoral-researcher-2/?feed_id=49076

#ProlongedFasting can help people injured by #CovidVaccines #Autophagy

https://www.naturalnews.com/2023-06-12-3-day-fast-reduce-inflammation-revitalize-immune-system.html

Postdoctoral Researcher

Icahn School of Medicine at Mount Sinai (ISMMS)

Come join us in the #LazarusLab as bio postdoc at #MountSinai #Autophagy #ChemicalBiology #NYC

See the full job description on jobRxiv: https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai-ismms-27778-postdoctoral-researcher-2/?feed_id=48502

#ScienceJobs #hiring #research
New York City #Un...
https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai-ismms-27778-postdoctoral-researcher-2/?feed_id=48502

#ProlongedFasting can help people injured by #CovidVaccines

https://www.naturalnews.com/2023-06-12-3-day-fast-reduce-inflammation-revitalize-immune-system.html

#Autophagy

Chloroplast protein import is controlled not just by the #ubiquitin-#proteasome system, but also by selective #NBR1-mediated selective #autophagy of translocon components in #Arabidopsis upon UV light or heat stress
https://www.embopress.org/doi/10.15252/embj.2022112534

Immune response to #TB infection determines disease outcomes. @RL_Kinsella @StallingsLab &co identify new roles for #autophagy in regulating proinflammatory responses of lung #macrophages to M. #tuberculosis infection #PLOSBiology https://plos.io/42GvBdn

#ProlongedFasting can help people injured by #CovidVaccines

https://newstarget.com/2023-06-12-3-day-fast-reduce-inflammation-revitalize-immune-system.html

#Autophagy

#ProlongedFasting can help people injured by #CovidVaccines

https://www.naturalnews.com/2023-06-12-3-day-fast-reduce-inflammation-revitalize-immune-system.html

#Autophagy

Want to learn how well-designed imaging experiments can unravel #autophagy fluxes? Then you should check @shah_ps's talk from tonight when it finishes processing: https://youtu.be/Z9gOZKx1x3w

#chemtwitter #biotwitter #cells #science #scicomm #STEM #openscience #Twitch #streaming #chemistrymastodon #ScienceMastodon #biomedical #biologymastodon #microscopy

Tonight at 10:30 PM EST, come learn about @shah_ps's work on dynamic #autophagy flux measurements for #biomedical applications!

twitch.tv/open_science

#chemtwitter #biotwitter #scicomm #STEM #openscience #streaming #science #ScienceTwitter #ScienceMastodon #chemistrymastodon #biologymastodon

https://autophagy.science/autophagy-without-fasting/ Autophagy regenerates every cell in your body, activates stem cells, brain, nerve, heart and lung tissues. Autophagy works with intermittent fasting to bring all your blood levels (glucose, A1C, pressure, cholesterol) to normal healthy levels faster than anything else, period. You can help autophagy work faster with autophagy boosters that allow your body to do it 3 times as fast. Get the amazing results of total body healing and renewal (deep tissue repair, nerves, brain tissue, autoimmune issues, cancer) and even DNA repair and stem cell activation by using specific autophagy supplements if you can't fast for long #autophagy #fasting #dna #stemcell

Researchers reveal how a #nanomachine cleans up inside the #cell.

#autophagy #cytoplasm

https://phys.org/news/2023-05-reveal-nanomachine-cell.html

https://autophagy.science/autophagy-supplements/ Autophagy regenerates every cell in your body, particularly damaged DNA cells (like those created by the covid-19 mRNA vaccines.) Autophagy is a natural process that happens when you fast (without protein consumption so it can rid your body of damaged protein chains (spike proteins) and rebuild healthy new cells. If you need healing ASAP then you will want to use Autophagy Activators that make the process happen faster and deeper. Repair your DNA and get full body cellular regeneration and deep healing on all levels. It works well during prolonged or intermittent fasting. Use it if you’re on a healthy ketogenic diet to enhance your healing and weight loss results dramatically. #autophagy #dna #regeneration #mRNA #healing

Referenced link: https://phys.org/news/2023-04-brain-cells-starved-energy-autophagy.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-04-brain-cells-starved-energy-autophagy.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1651631383712866304#m

#Braincells are starved of energy in #autophagy dysfunction, new study finds @CellReports https://linkinghub.elsevier.com/retrieve/pii/S2211124723003832 https://phys.org/news/2023-04-brain-cells-starved-energy-autophagy.html

Autophagy in Spinocerebellar Ataxia Type 3: From Pathogenesis to Therapeutics

#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Ataxia #SpinocerebellarAtaxia #SCA3 #MachadoJosephDisease #Neuroprotection #Neuropharmacology #Neurotherapeutics #Autophagy

https://www.mdpi.com/1422-0067/24/8/7405