Genetic changes sustaining the development of #CancerOfUnknownPrimary (CUP) remain elusive. New study reports a novel activating mutation of the #AxonGuidance gene #PLXNB2 that sustains proliferative autonomy and confers invasive properties to CUP stem cells, in EGFR-dependent manner.
By E. Giraudo, L. Tamagnone & colleagues
#cancerofunknownprimary #axonguidance #plxnb2
The #Cerebellin family of proteins is known to influence #Synapse formation & function. @le_mccorm & @stephgupton1 explore a #PLOSBiology study that identifies a new role for Cerebellin-1 in #AxonGuidance. Primer: https://plos.io/3VdLdBF Paper: https://plos.io/3ghYJ8M
#axonguidance #plosbiology #synapse #cerebellin
The #Cerebellin family of proteins is known to influence #Synapse formation & function. @le_mccorm & @stephgupton1 explore a #PLOSBiology study that identifies a new role for Cerebellin-1 in #AxonGuidance. Primer: https://plos.io/3VdLdBF Paper: https://plos.io/3ghYJ8M
#axonguidance #plosbiology #synapse #cerebellin
The #Cerebellin family of proteins is known to influence #Synapse formation & function. @le_mccorm & @stephgupton1 explore a #PLOSBiology study that identifies a new role for Cerebellin-1 in #AxonGuidance. Primer: https://plos.io/3VdLdBF Paper: https://plos.io/3ghYJ8M
#axonguidance #plosbiology #synapse #cerebellin
Because the search function here doesn't work so well, as I've seen others do, here is a list of hashtags # I'm following (some of which I'm also adding to my profile):
#DevBio
#DevBiol
#Development
#Myoverse (as a possible equivalent of #Myotwitter )
#Morphogenesis
#Regeneration #MuscularDystrophy
#FSHD
#Mechanobiology
#CellBiology
#Neurobiology
#NeuroDev
#Imaging
#biorxiv
#preLights
#Microscopy
#axonguidance
#axonguidance #microscopy #prelights #biorxiv #imaging #neurodev #neurobiology #CellBiology #mechanobiology #fshd #MuscularDystrophy #regeneration #morphogenesis #myotwitter #myoverse #Development #devbiol #devbio
#introduction Iām Anne, Professor in #neuroscience at Fribourg University. In our #Drosophila lab, we work on neuronal circuits for reproductive behavior and acoustic communication, sex differences of the nervous system and the signaling function of seminal fluid. I like #arthopods #sexualselection #matechoice #spermcompetition #microscopy and #connectomics
Used to work with #zebrafish #development #axonguidance
Also teaching and keen on #embryology and #histology for medical students...
#introduction #neuroscience #drosophila #arthopods #sexualselection #matechoice #spermcompetition #microscopy #connectomics #zebrafish #development #axonguidance #embryology #histology