Benjamin Carr, Ph.D. 👨🏻💻🧬 · @BenjaminHCCarr
1026 followers · 2675 posts · Server hachyderm.io
Global #COVID monitoring is crashing as BA.2.86 #COVIDvariant raises alarm
The number of mutations in #BA2.86's critical #spikeprotein is over 30, rivaling the number seen in the original omicron subvariant, #BA1, which went on to cause a tidal wave of cases and hospitalizations. The spike mutations appear geared toward evading neutralizing #antibody protections built up from past infections and #vaccinations.
"This is on the shoulders of governments right now." https://arstechnica.com/health/2023/08/global-covid-monitoring-is-crashing-as-ba-2-86-variant-raises-alarm/
#covid #covidvariant #ba2 #spikeprotein #ba1 #antibody #vaccinations
Giuseppe Michieli · @GMIK69
68 followers · 1519 posts · Server mstdn.science[Articles] #Omicron #BA1-containing #mRNA-1273 #boosters compared with the original #COVID19 #vaccine in the #UK: a randomised, observer-blind, active-controlled trial https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00295-5/fulltext?rss=yes #prevention #publichealth #rct
#omicron #ba1 #mrna #boosters #COVID19 #vaccine #uk #prevention #publichealth #RCT
Giuseppe Michieli · @GMIK69
68 followers · 1497 posts · Server mstdn.science
Giuseppe Michieli · @GMIK69
68 followers · 1491 posts · Server mstdn.science''In this study, the authors isolated and characterized neutralizing antibodies from vaccinated individuals with #SARS-CoV-2 #BA1 breakthrough infection and show that elite antibodies derived from specific germlines provide potent pan-variant neutralization capacity and in vivo protection.''
Giuseppe Michieli · @GMIK69
69 followers · 1438 posts · Server mstdn.scienceNeutralising #immunity to #omicron sublineages #BQ11, #XBB, and #XBB15 in healthy #adults is boosted by bivalent #BA1-containing #mRNA #vaccination and previous Omicron infection, https://doi.org/10.1016/S1473-3099(23)00289-X
#immunity #omicron #bq11 #xbb #xbb15 #adults #ba1 #mrna #vaccination
Enville · @enville
11 followers · 14 posts · Server synthwave.social
Enville · @enville
11 followers · 13 posts · Server synthwave.socialAnd here's #AlexReid's review of the #BA1! Totaly love that this synth is based on Yamaha’s battery powered CS-01 (and that you can virtually emulate the BA-1‘s battery strength! Crazy!) 💜 #BabyAudio https://youtu.be/Tc_dtOXoOC4
Enville · @enville
11 followers · 12 posts · Server synthwave.social
Enville · @enville
11 followers · 11 posts · Server synthwave.socialThe first ever #BabyAudio-Synth #BA1 is out tuesday and I can’t wait to get my hands on this 😱 https://youtu.be/N1UMtGVPkvg
Giuseppe Michieli · @GMIK69
54 followers · 968 posts · Server mstdn.science#Immunity of heterologous and homologous boosted or #convalescent individuals against #Omicron #BA1, #BA2 and #BA4/5 variants https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiad057/7069351?rss=1
#immunity #convalescent #omicron #ba1 #ba2 #BA4
Giuseppe Michieli · @GMIK69
54 followers · 968 posts · Server mstdn.science{#SARS-CoV-2 #Omicron} #BA1, #BA2 and #BA275 variants show comparable #replication kinetics, reduced impact on #epithelial #barrier and elicit cross-neutralizing #antibodies https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1011196
#sars #omicron #ba1 #ba2 #ba275 #replication #epithelial #barrier #antibodies
Lorraine · @Lorrrraaaaine
354 followers · 1448 posts · Server zeroes.cahttps://www.news-medical.net/news/20230201/New-study-suggests-Omicron-BA1-breakthrough-infection-drives-long-term-remodeling-of-memory-B-cell-repertoire-in-vaccinated-populations.aspx
#BA1
think these studies are all supposed to be “comforting & reassuring” but having had #sarscov2 1.0 aka🇨🇳via🇮🇹then 2 #Pfizer & then BA.1…
trust my remodeled #bCells as much as I trust my psychopath 1/2 brother🙄,which is to say, negative quadrillion
BA.1 drove me into 24/7 obsession w/ #reinfection & all things #Covid
& after nearly catching BA.5 imo it’s either avoid like the Plague it is or suffer lifelong consequences
We need updated & better #vaccines #Novavax 💉💉💉💉
#ba1 #sarscov2 #pfizer #Bcells #reinfection #covid #vaccines #novavax
DMZ · @dmz
637 followers · 1250 posts · Server swiss-talk.netDE: #Herzmuskelzellen hören früher auf zu schlagen – #Omicron-#Subvariante BA.5 schädigt #Kardiomyozyten stärker als BA.1 https://www.mittellaendische.ch/2023/01/26/de-herzmuskelzellen-h%C3%B6ren-fr%C3%BCher-auf-zu-schlagen-omicron-subvariante-ba-5-sch%C3%A4digt-kardiomyozyten-st%C3%A4rker-als-ba-1/ #BA1 #BA5 #CovidIsNotOver #Corona #Pandemie #Wissenschaft #Forschung #Fakten #DMZ
#herzmuskelzellen #omicron #subvariante #kardiomyozyten #ba1 #ba5 #covidisnotover #corona #pandemie #wissenschaft #forschung #fakten #dmz
Giuseppe Michieli · @GMIK69
54 followers · 970 posts · Server mstdn.science#Spike and #nsp6 are key determinants of #SARS-CoV-2 #Omicron #BA1 #attenuation https://www.nature.com/articles/s41586-023-05697-2
#spike #nsp6 #sars #omicron #ba1 #attenuation
Giuseppe Michieli · @GMIK69
54 followers · 970 posts · Server mstdn.science#Protection conferred by #Delta and #BA1 / #BA2 #infection against #BA4 / #BA5 infection and #hospitalization: A Retrospective Cohort Study, The Journal of Infectious Diseases, jiad003, https://doi.org/10.1093/infdis/jiad003
#protection #delta #ba1 #ba2 #infection #BA4 #BA5 #Hospitalization
Protect our Province BC · @protect_bc
389 followers · 84 posts · Server zeroes.ca
Giuseppe Michieli · @GMIK69
54 followers · 970 posts · Server mstdn.scienceLi, M., Ren, Y., Aw, Z.Q. et al. Broadly neutralizing and protective #nanobodies against #SARS-CoV-2 #Omicron subvariants #BA1, #BA2, and #BA4/5 and diverse #sarbecoviruses. Nat Commun 13, 7957 (2022). https://doi.org/10.1038/s41467-022-35642-2
#Nanobodies #sars #omicron #ba1 #ba2 #BA4 #sarbecoviruses
Eric's Risk Assessment · @EricCarroll
1625 followers · 1860 posts · Server zeroes.ca
Strong attenuation of #SARSCoV2 #Omicron #BA1 and increased replication of the #BA5 subvariant in human cardiomyocytes
h/t Globalbiosec: "Whilst BA.1 is less pathogenic to heart muscle than #Delta, BA.5 is similar to Delta. Important study that shows the tendency of #SARSCoV2 to directly damage cardiomyocytes, the cells that make up your heart muscle."
#sarscov2 #omicron #ba1 #BA5 #delta
Giuseppe Michieli · @GMIK69
54 followers · 970 posts · Server mstdn.science
Giuseppe Michieli · @GMIK69
5 followers · 113 posts · Server mstdn.scienceBoon ACM, Darling TL, Halfmann PJ, Franks J, Webby RJ, Barouch DH, et al. (2022) Reduced #airborne #transmission of #SARS-CoV-2 #BA1 #Omicron virus in Syrian #hamsters. PLoS Pathog 18(12): e1010970. https://doi.org/10.1371/journal.ppat.1010970
#airborne #transmission #sars #ba1 #omicron #hamsters