Global monitoring is crashing as BA.2.86 raises alarm
The number of mutations in .86's critical is over 30, rivaling the number seen in the original omicron subvariant, , which went on to cause a tidal wave of cases and hospitalizations. The spike mutations appear geared toward evading neutralizing protections built up from past infections and .
"This is on the shoulders of governments right now." arstechnica.com/health/2023/08

#covid #covidvariant #ba2 #spikeprotein #ba1 #antibody #vaccinations

Last updated 1 year ago

Giuseppe Michieli · @GMIK69
74 followers · 1619 posts · Server mstdn.science

Associations of with subvariants and , host status, and outcomes in : a registry-based observational study - Lancet ID.: doi.org/10.1016/S1473-3099(23)

#COVID19 #symptoms #omicron #ba2 #BA5 #clinical #japan #epidemic #pandemic #epidemiology

Last updated 1 year ago

Giuseppe Michieli · @GMIK69
73 followers · 1605 posts · Server mstdn.science
Giuseppe Michieli · @GMIK69
70 followers · 1375 posts · Server mstdn.science
Giuseppe Michieli · @GMIK69
55 followers · 1016 posts · Server mstdn.science
Leigh Dodds · @ldodds
530 followers · 775 posts · Server mastodon.me.uk

We've had a good couple of inches of snow, and it's still snowing

#uksnow #ba2

Last updated 2 years ago

Giuseppe Michieli · @GMIK69
54 followers · 968 posts · Server mstdn.science
Giuseppe Michieli · @GMIK69
54 followers · 968 posts · Server mstdn.science
Eric's Risk Assessment · @EricCarroll
1858 followers · 2628 posts · Server zeroes.ca

Associations of Symptoms with and , Host Status, and Clinical Outcomes: A Registry-Based Observational Study in Sapporo, Japan

- BA.5 infection associated with higher symptom burden than BA.2
- Omicron breakthrough-infected individuals with ≥ 3 vaccinations or previous infection were less likely to exhibit systemic symptoms, but more likely to exhibit upper respiratory symptoms.

medrxiv.org/content/10.1101/20

#covid19 #omicron #subvariants #ba2 #BA5 #sarscov2 #SARS2

Last updated 2 years ago

Eric Carroll · @EricCarroll
520 followers · 317 posts · Server toad.social

Associations of Symptoms with and , Host Status, and Clinical Outcomes: A Registry-Based Observational Study in Sapporo, Japan

- BA.5 infection associated with higher symptom burden than BA.2
- Omicron breakthrough-infected individuals with ≥ 3 vaccinations or previous infection were less likely to exhibit systemic symptoms, but more likely to exhibit upper respiratory symptoms.

medrxiv.org/content/10.1101/20

#COVID19 #Omicron #subvariants #ba2 #BA5 #SarsCoV2 #SARS2

Last updated 2 years ago

Jim Cappio · @DrPrunesquallor
63 followers · 1398 posts · Server mstdn.social

RT @DrEricDing
Dr Monica Gandhi has been infamously anti-precautionary & anti-mitigation & wrong time and again. She now wants to end more mitigations—all while deaths highs, & rising. So @mehdirhasan checks her record—& asks if she’d stop making forecasts:

#ba2 #Omicron

Last updated 2 years ago

Giuseppe Michieli · @GMIK69
54 followers · 968 posts · Server mstdn.science
Klaus Jürgen :archlinux: · @kluergen
223 followers · 115 posts · Server social.tchncs.de

Die Variante feiert ein erstaunliches Comeback, während BA5 weiter zurückgeht. Ich frag mich ob das nur an dem angepassten liegt.

#impfstoff #ba2 #Omikron

Last updated 2 years ago

Giuseppe Michieli · @GMIK69
54 followers · 970 posts · Server mstdn.science

conferred by and / against / infection and : A Retrospective Cohort Study, The Journal of Infectious Diseases, jiad003, doi.org/10.1093/infdis/jiad003

#protection #delta #ba1 #ba2 #infection #BA4 #BA5 #Hospitalization

Last updated 2 years ago

Giuseppe Michieli · @GMIK69
54 followers · 970 posts · Server mstdn.science

''It is worth noting that is not a virus mutation, but a strain of two lineages, and . In contrast, the previous major epidemic strains in the United States, BQ.1 and BQ.1.1, both evolved from BA.5.''

#xbb #recombinant #ba2 #ba2101 #ba275

Last updated 2 years ago

Giuseppe Michieli · @GMIK69
54 followers · 970 posts · Server mstdn.science

Li, M., Ren, Y., Aw, Z.Q. et al. Broadly neutralizing and protective against -CoV-2 subvariants , , and /5 and diverse . Nat Commun 13, 7957 (2022). doi.org/10.1038/s41467-022-356

#Nanobodies #sars #omicron #ba1 #ba2 #BA4 #sarbecoviruses

Last updated 2 years ago

Giuseppe Michieli · @GMIK69
54 followers · 970 posts · Server mstdn.science
Giuseppe Michieli · @GMIK69
54 followers · 970 posts · Server mstdn.science

Rössler, A., Netzl, A., Knabl, L. et al. and differ immunologically from both omicron and pre-omicron . Nat Commun 13, 7701 (2022). doi.org/10.1038/s41467-022-353

#ba2 #BA5 #omicron #ba1 #variants

Last updated 2 years ago

Giuseppe Michieli · @GMIK69
4 followers · 51 posts · Server mstdn.science

against symptomatic with () and () and -CoV-2 after previous and in in , August, 2021–March, 2022: a national, observational, test-negative, case-control study, doi.org/10.1016/S1473-3099(22)

#protection #infection #delta #b16172 #omicron #b11529 #ba1 #ba2 #sars #variants #vaccination #adolescents #england

Last updated 2 years ago

Petra van Cronenburg · @NatureMC
535 followers · 1435 posts · Server mastodon.online

Study in Nature: Enhanced of in human and organoids: BA.2 replicated more efficiently & triggered substantially higher levels of (cell death) in the infected human forebrain and midbrain organoids. nature.com/articles/s41392-022

#apoptosis #midbrain #forebrain #ba2 #Omicron #sarscov2 #replication

Last updated 2 years ago