This is intriguing: phage therapy induces bacterial resistance but also reduced virulence.
So clinical benefit post-phage could also stem from bacterial attenuation rather than just eradication.
Question is how sustainable this effect may be.
#Phages #bacteria #microbiology #IDMastodon #medicine #MedMastodon #AMR #antibiotics #bacteriophage
https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(23)00405-6/fulltext?dgcid=raven_jbs_aip_email
#phages #bacteria #microbiology #IDMastodon #medicine #MedMastodon #AMR #antibiotics #bacteriophage
The First rule of Phage Naming Club is exceedingly disappointing.
#Science #Virology #Bacteriophage #Research
https://phagesdb.org/namerules/
#Science #virology #bacteriophage #research
Bacteriophages: The 'good viruses' that fight bacteria
#bacteria #virus #antibioticresistance #infectiousdisease #microbiome #healthcare #phage #bacteriophage
#bacteriophage #phage #healthcare #microbiome #infectiousdisease #antibioticresistance #virus #bacteria
A phabulous plush phage gift from my friend Mark Martin #phage #bacteriophage #science #microbiology Check out those adorable phangs!
#phage #bacteriophage #Science #microbiology
Antibiotic resistance at the forefront again and the issue of dealing with specific resistant bacteria without harming the beneficial ones in your system.
Hence antibacterials are out, but what about targeted bacteriophages?
Researchers in Denmark have engineered a phage with CRISPR that targets only E. coli to protect the microbiome from harm.
#Resistance #Disease #Antibiotics #Ecoli #Denmark #Bacteriophage #Phage #CRISPR #Science #Biotech #Biotechnology #Scicomm
#resistance #disease #antibiotics #Ecoli #denmark #bacteriophage #phage #crispr #Science #biotech #biotechnology #scicomm
Engineering the #bacteriophage T4 to serve as a vector for molecular #repair.
https://phys.org/news/2023-05-bacteriophage-t4-vector-molecular.html
Researchers complete first-ever mapping of human #gut #virus.
#crassvirales #bacteriophage #DNA #genomics
https://phys.org/news/2023-05-first-ever-human-gut-virus.html
#gut #virus #crassvirales #bacteriophage #dna #genomics
Ars Technica: Thousands of unknown viruses discovered in baby poo—and that’s not bad news https://arstechnica.com/?p=1936296 #Tech #arstechnica #IT #Technology #bacteriophage #immunology #Science #virus #poop
#Tech #arstechnica #it #technology #bacteriophage #immunology #science #Virus #poop
Thousands of unknown viruses discovered in baby poo—and that’s not bad news - Enlarge (credit: LSOphoto via Getty)
An international team of ... - https://arstechnica.com/?p=1936296 #bacteriophage #immunology #science #virus #poop
#poop #virus #science #immunology #bacteriophage
×-posting https://twitter.com/christo71213435/status/1649731454526447616?t=IcIbj-5Cbtk6fkdPj66TQw&s=19
"We have never quantified those benefits and costs...." (abstract)
except that Wang et al (2010) did this in one individual case...
[pubmed.ncbi.nlm.nih.gov/21266997/] mentioned here >
schaechter.asmblog.org/schaechter/201…
@linsalrob
New discovery stops #bacterial #virus #contamination.
https://phys.org/news/2023-04-discovery-bacterial-virus-contamination.html
#bacterial #virus #contamination #bacteriophage
🆕 Episode of #Breakpoints
Drs. Saima Aslam and Daria Van Tyne join Dr. Rachel Britt for a discussion all about #bacteriophage therapy!
In the era of #antimicrobialresistance, this is an episode you won’t want to miss
🎧 Listen now: https://sidp.pinecast.co/
#IDMastodon #TooteRx #IDTooter #MastodonRx
#breakpoints #bacteriophage #antimicrobialresistance #IDMastodon #TooteRx #idtooter #MastodonRx
The 'Rapunzel' #virus: An #evolutionary oddity.
https://phys.org/news/2023-03-rapunzel-virus-evolutionary-oddity.html
#virus #Evolutionary #bacteriophage
RT @cellhostmicrobe
Hna confers #phage resistance. #Bacteriophage defense system “Hna” consisting of single predicted helicase/nuclease confers protection by abortive infection. Hna homologs present in array of #bacteria, including medically or agriculturally relevant species https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(23)00035-5
#phage #bacteriophage #bacteria
You might also be interested in The Lancet Microbe's latest editorial:
The unregulated potential of phages
https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(23)00043-5/fulltext
Bacteria-killing viruses could combat antibiotic resistance, says UK scientist
Enhancing #bacteriophage therapeutics through in situ production and release of heterologous antimicrobial effectors | bioRxiv
A perfect fit: #Bacteriophage receptor-binding proteins for diagnostic and therapeutic applications - #phage
https://www.sciencedirect.com/science/article/pii/S1369527422001242
The March issue of The Lancet Microbe is now online:
https://thelancet.com/journals/lanmic/issue/current
The journal is #OpenAccess, so you are free to explore all its content, but these hashtags offer a flavour:
#bacteriophage #phage #SARSCoV2 #COVID19 #AMR #CRPA #Pseudomonas #Ebola #SudanVirus #metagenomics #OA
#oa #Metagenomics #sudanvirus #ebola #Pseudomonas #crpa #AMR #COVID19 #SarsCoV2 #phage #bacteriophage #openaccess
Pharokka: a fast scalable #bacteriophage annotation tool | #Bioinformatics
https://academic.oup.com/bioinformatics/article/39/1/btac776/6858464?login=false
#bioinformatics #bacteriophage