Interesting conclusions about drug discovery. Barabasi, as always, involved in complexity networks phenomena:

The Clinical Trials Puzzle: How Network Effects Limit Drug Discovery
https://arxiv.org/abs/2301.10709v1

[...] We find that convention dominates over innovation, as over 96% of the recorded trials focus on previously tested drug targets, and the tested drugs target only 12% of the human interactome. If current patterns persist, it would take 170 years to target all druggable proteins. We uncover two network-based fundamental mechanisms that currently limit target discovery: preferential attachment, leading to the repeated exploration of previously targeted proteins; and local network effects, limiting exploration to proteins interacting with highly explored proteins.

#information_networks #complexity #barabasi #drug_discovery #search_strategy

@ct_bergstrom I was trained in industrial organizational #psychology, and one of the fundamental tenets in the field is that any simple measure is invalid.
This book explains it using big data and network theory. The comment about it being an MBA trick is spot on.
https://barabasi.com/book/linked_,
Neither you, nor your work can ever be boiled down so simply. #science #barabasi