What are the clinically meaningful ways of looking at tumor RNA-Seq?

Well, there are too many to count. But we show that RNA-Seq could be a good proxy for CD8+ T-cell localization within a tumor. (poster for #bc2 is here: https://bc2.ch/posters/gallery/169)

Why is this localization important? Immune phenotypes or spatial distribution of CD8+ T cells in the tumor microenvironment turns out to be predictive of treatment outcome in many indications (more here: https://doi.org/10.1016/j.immuni.2019.12.011).

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A few days left to register with early bird rate to our #BC2 #ISBSIB workshop "Standardization of single-cell metadata: an Open Research Data initiative" with Jason Hilton of #cellxgene & David Osumi-Sutherland #EBI #SingleCell #FAIRdata #bioinformatics #biocuration #HumanCellAtlas #FlyCellAtlas https://www.bc2.ch/tutorials-workshops