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Ewa Zarnowska · @ewadorotaz
217 followers · 29 posts · Server mastodon.world

@NeuroDrugDoc also need gamma subunit to work

#benzodiazepines

Last updated 2 years ago

🧠 are positive allosteric modulators and require the presence of GABA to work! Their effects are mediated by the α subunit.

● Anxiolytics - α2, α3
● Sedatives - α1, α5
● Anticonvulsants - α1, α2, α3, α5
● Anterograde amnesia - α1

α4 and α6 do not bind benzodiazepines
● Possess arginine where other α subunits have histidine

2/2 thread

#benzodiazepines #PharmPhriday #gaba

Last updated 2 years ago

EU drugs agency · @emcdda
8 followers · 215 posts · Server respublicae.eu

The EMCDDA is currently monitoring 33 new benzodiazepines through the EU Early Warning System on NPS. Three of these were reported for the first time in 2021. Explore our interactive infographic on new benzodiazepines: ow.ly/IlfZ50JYWQX

🐦🔗: nitter.eu/EMCDDA/status/155187

#benzodiazepines #ews25 #NPS

Last updated 2 years ago

Muninn 🍃 · @muninn
336 followers · 2730 posts · Server social.coop

The more research I read the more leery I get of ("" like xanax, valium, etc) and (including allergy pills like benadryl & even some "non-drowsy" , and other ).

The short term cognitive impacts are well known. The cumulative risk? Not so many people have heard of that. But the evidence so far looks bad.

#benzodiazepines #benzos #anticholinergics #antihistamines #drugs #dementia

Last updated 7 years ago