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Spatially-resolved profiling of the T-cell receptor repertoire in archival clinical specimens using FUME-TCRseq https://biorxiv.org/cgi/content/short/2023.04.24.538037v1 #biorxiv_immuno
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Genome-wide characterization of T cell responses to Bordetella pertussis reveals broad reactivity and similar polarization ... https://biorxiv.org/cgi/content/short/2023.03.24.534182v1 #biorxiv_immuno
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Clonal associations of lymphocyte subsets and functional states revealed by single cell antigen receptor profiling of T and B cells ... https://biorxiv.org/cgi/content/short/2023.03.18.533282v1 #biorxiv_immuno
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TLR7 activation at epithelial barriers promotes emergency myelopoiesis and lung anti-viral immunity https://biorxiv.org/cgi/content/short/2023.02.06.527328v1 #biorxiv_immuno
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Mechanism of glycoform specificity and protection against antibody dependent enhancement by an anti-afucosylated IgG nanobody https://biorxiv.org/cgi/content/short/2023.01.23.525277v1 #biorxiv_immuno
Another interesting preliminary evidence from a broadly neutralizing antibody able to recognize N-glycans at the HIV-1 gp120 surface...
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Recognition determinants of broad and potent HIV-1 neutralization by an affinity matured antibody from a pediatric elite-neutralizer https://biorxiv.org/cgi/content/short/2023.01.19.524673v1 #biorxiv_immuno
🐦🔗: https://twitter.com/biorxiv_immuno/status/1616636475906396161
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Recognition determinants of broad and potent HIV-1 neutralization by an affinity matured antibody from a pediatric elite-neutralizer https://biorxiv.org/cgi/content/short/2023.01.19.524673v1 #biorxiv_immuno
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Human Bone Marrow Plasma Cell Atlas: Maturation and Survival Pathways Unraveled by Single Cell Analyses https://biorxiv.org/cgi/content/short/2023.01.18.524601v1 #biorxiv_immuno
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Corynebacterium diphtheriae causes keratinocyte-intrinsic ribotoxic stress and NLRP1 inflammasome activation in a model of cutaneous ... https://biorxiv.org/cgi/content/short/2023.01.16.524188v1 #biorxiv_immuno
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Salmonella cancer therapy metabolically disrupts tumours at the collateral cost of T cell immunity https://biorxiv.org/cgi/content/short/2023.01.12.523780v1 #biorxiv_immuno
🐦🔗: https://twitter.com/biorxiv_immuno/status/1614129596491767808
RT Paul Ogongo
Our latest work show #IL17 #CD4 #Tcells are preserved in HIV-ART. We identify two subsets of #Th17 cells; 1 specifically enriched for IL17 production to #Mtb but not CMV or SEB; and link between IDO-1 activity and circulating Th17 cells.@AnthonyVanTran @UCSF_EXPM @UCSF_GIVI_CFAR
M. tuberculosis antigen-responsive IL17+ CD4 T cells are disproportionately spared in ART-suppressed HIV biorxiv.org/cgi/content/sh… #biorxiv_immuno
#IL17 #cd4 #TCells #th17 #mtb #biorxiv_immuno
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KLRG1 marks tumor-infiltrating CD4 T cell subsets associated with tumor progression and immunotherapy response https://biorxiv.org/cgi/content/short/2023.01.01.522340v1 #biorxiv_immuno
🐦🔗: https://twitter.com/biorxiv_immuno/status/1610007160108322816
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T-cell cellular stress and reticulocyte signatures, but not loss of naive T lymphocytes, characterize severe COVID-19 in older adults https://biorxiv.org/cgi/content/short/2022.12.21.521463v1 #biorxiv_immuno
🐦🔗: https://twitter.com/biorxiv_immuno/status/1606111385582280706
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Co-evolution of human influenza A and Epstein Barr virus-specific CD8 ex vivo memory T cell receptor BV repertoires with increasing age https://biorxiv.org/cgi/content/short/2022.12.15.520600v1 #biorxiv_immuno
🐦🔗: https://twitter.com/biorxiv_immuno/status/1604661943473737731
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Spatial transcriptomics of T and B cell receptors uncovers lymphocyte clonal dynamics in human tissue. https://biorxiv.org/cgi/content/short/2022.11.22.516865v1 #biorxiv_immuno
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Spatial transcriptomics of T and B cell receptors uncovers lymphocyte clonal dynamics in human tissue. https://biorxiv.org/cgi/content/short/2022.11.22.516865v1 #biorxiv_immuno
🐦🔗: https://twitter.com/biorxiv_immuno/status/1595828852479381504