Classification of formalin-fixed bladder cancer cells with laser tweezer Raman spectroscopy.
Analyst, 2023, Advance Article
https://doi.org/10.1039/D3AN00119A
#ramaneffect #bladdercancer #cancer #openaccess

Point-of-Care Diagnosis of Bladder Cancer With Vibrational Spectroscopy: A Systematic Review.
Société Internationale d’Urologie Journal, 4(4), 321-334.
https://doi.org/10.48083/10.48083/NCZW3015
#bladdercancer #cancer #review

RT @htlifeandstyle: #Health experts reveal all you need to know about #bladdercancer - what #symptoms to look for, how to distinguish between #infection and #cancer and its #treatments
@htTweets

https://www.hindustantimes.com/lifestyle/health/bladder-cancer-symptoms-to-look-for-to-distinguish-between-infection-and-cancer-101689400031375.html #press

“The study, published today in the journal Nature, found that loss of the Y chromosome helps cancer cells evade the body's immune system. This common impact of the aging process in men results in aggressive bladder cancer, but somehow also renders the disease more vulnerable—and responsive—to a standard treatment called immune checkpoint inhibitors.” #dna #epigenetics #ychromosome #bladdercancer #geneadons #isogg
https://medicalxpress.com/news/2023-06-loss-chromosome-men-enables-cancer.amp

Today I’m at the UK Oncology Forum #OF23 in Birmingham, talking about the World Bladder Cancer Patient Coalition's 45 country survey. Only 16% of people with #BladderCancer received information about #ClinicalTrials. People with advanced or metastatic bladder cancer were likelier to participate in a trial.

THAT WAS THE LAST SHOW

https://davidguilbault.substack.com/p/that-was-the-last-show?sd=pf

#cancer #bladdercancer #tumor #bladderresection #cancerfree #singersongwriter #substack #substacknewsletter #substacknotes #originalmusic #musicvideo #musicvideos #liveconcert #concert #livemusic #clubdate

Referenced link: https://medicalxpress.com/news/2023-05-bladder-cancer-classification-treatment-response.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-05-bladder-cancer-classification-treatment-response.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1661474810738745348#m

RT by @physorg_com: New #bladdercancer classification predicts treatment response @sciencetm https://www.science.org/doi/10.1126/scitranslmed.abn4118 https://medicalxpress.com/news/2023-05-bladder-cancer-classification-treatment-response.html

Check out some #CoolScienceImages from a Nature Communications study on #fluorescencefriday. Nikolos et al. showed that an iDAMP blockade approach synergizes with #chemotherapy and sensitizes #bladdercancer to #immunotherapy in #preclinicalmodels.

https://www.nature.com/articles/s41467-022-29026-9

Music: Baby Don’t Hurt Me by David Guerra, Anne-Marie, & Coi Leray

#CancerMoonshot
#CancerMoonshotSeminar
#CMSSChan
#cancerresearch
#ImmuneCheckpointBlockade

In a discovery that could improve the survival of #BladderCancer patients, Northwestern Medicine scientists have developed a biomarker signature test to predict which tumors will respond to #Immunotherapy

https://t.co/vprgjVmMXA

Referenced link: https://medicalxpress.com/news/2023-03-bladder-cancer-cells-common-genetic.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-03-bladder-cancer-cells-common-genetic.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1641795753889636358#m

RT by @physorg_com: Different types of #bladdercancer #cells share common genetic ancestry @penn_state @NatureComms https://www.nature.com/articles/s41467-022-34251-3 https://medicalxpress.com/news/2023-03-bladder-cancer-cells-common-genetic.html

RT @TumorBoardTues
Join us here on #TumorBoardTuesday for a UK-led #BladderCancer case from👨🏻‍⚕️ @tompowles1👩🏼‍⚕️ @drfrankiejs

📅Tues, 03/28/23 at🕗8PM ET / 12AM 🇬🇧
FREE #CME👉🏽http://integrityce.com/tbt 👈🏼

💬A way to gather input is with📊, so b4️⃣ their case, tell us where you are in your 🩺 journey
👇🏽

RT @BartsECMC
@TumorBoardTues 1/15 #TumorBoardTuesday #BladderCancer #OncTwitter
75yo👴🏽
HTN: Amlodipine
T2DM: Metformin, Insulin
6 mo: haematuria & weight loss
CTCAP: thickened bladder wall with L side hydronephrosis & borderline paraaortic LNS. No distant mets
TURBT: G3 PT2N1M0 bladder TCC
CrCl: 75ml/min

RT @BartsECMC
@TumorBoardTues 2/15 #TumorBoardTuesday #BladderCancer @tompowles1 @MPishvaian @JohnEbbenMDPhD

👴🏽 Patient opts for cystectomy.

🤔 Should we do a PET scan prior to surgery? Why or why not?

RT @BartsECMC
@TumorBoardTues @tompowles1 @MPishvaian @JohnEbbenMDPhD 3/15 #TumorBoardTuesday #BladderCancer

❌PET scan prior to✂️
🩻PET lacks sensitivity in MIBC (70% in prior study n=43)
📚@adamkibel_uro https://pubmed.ncbi.nlm.nih.gov/19652070/
clinically negative CT + bone scan, PET/CT had SNS of 70% in MIBC
🧑🏻‍⚕️🤝👴🏽 #SharedDecision 4 cycles neoadju gem+cis

RT @BartsECMC
@TumorBoardTues @tompowles1 @MPishvaian @JohnEbbenMDPhD @adamkibel_uro 4/15 #TumorBoardTuesday #BladderCancer

🩻 CTCAP shows small reduction in lymph nodes and bladder tumour after 4 cycles NA chemotherapy

👴🏽Patient proceeded to surgery.
pT3N0 disease

🧐 Should we measure ctDNA?

RT @BartsECMC
@TumorBoardTues @tompowles1 @MPishvaian @JohnEbbenMDPhD @adamkibel_uro @DrChoueiri @cdanicas @drenriquegrande @SCUColombia @wroclawski_uro @raymanneh @T_AlonsoGordoa @hannahdzmd @sandysrimd @sumitshahMD @MattGalsky @OncoBellmunt @y_loriot @PGrivasMDPhD 12/15 #TumorBoardTuesday #BladderCancer

Considering all of the above information and criteria.

🤨 What would you do next?

RT @BartsECMC
@TumorBoardTues @tompowles1 @MPishvaian @JohnEbbenMDPhD @adamkibel_uro @DrChoueiri @cdanicas @drenriquegrande @SCUColombia @wroclawski_uro @raymanneh @T_AlonsoGordoa @hannahdzmd @sandysrimd @sumitshahMD @MattGalsky @OncoBellmunt @y_loriot @PGrivasMDPhD 13/15 #TumorBoardTuesday #BladderCancer

In this case, the answer is Enfortumab Vedotin (✨EV301)

📚@tompowles1 @DrRosenbergMSK https://clinicaltrials.gov/ct2/show/NCT03474107
📚 https://www.nejm.org/doi/full/10.1056/NEJMoa2035807

RT @BartsECMC
@TumorBoardTues @tompowles1 @MPishvaian @JohnEbbenMDPhD @adamkibel_uro @DrChoueiri @cdanicas @drenriquegrande @SCUColombia @wroclawski_uro @raymanneh @T_AlonsoGordoa @hannahdzmd @sandysrimd @sumitshahMD @MattGalsky @OncoBellmunt @y_loriot @PGrivasMDPhD @DrRosenbergMSK 14/15 #TumorBoardTuesday #BladderCancer

Following Cycle 3, Day 1 treatment with EV, 👴🏽 patient develops some mild G2 skin toxicity.

🤨How do you proceed to treat this patient?

RT @BartsECMC
@TumorBoardTues @tompowles1 @MPishvaian @JohnEbbenMDPhD @adamkibel_uro @DrChoueiri @cdanicas @drenriquegrande @SCUColombia @wroclawski_uro @raymanneh @T_AlonsoGordoa @hannahdzmd @sandysrimd @sumitshahMD @MattGalsky @OncoBellmunt @y_loriot @PGrivasMDPhD @DrRosenbergMSK 15/15 #TumorBoardTuesday #BladderCancer

👴🏽Patient is now in remission🎉
> 60% reduction in target lesions

🔮We are planning to continue EV until possible progression
🤔 Do you agree with this approach?

RT @BartsECMC
@TumorBoardTues @tompowles1 @MPishvaian @JohnEbbenMDPhD 3/15 #TumorBoardTuesday #BladderCancer

❌PET scan prior to✂️
🩻PET lacks sensitivity in MIBC (70% in prior study n=43)
📚@adamkibel_uro https://pubmed.ncbi.nlm.nih.gov/19652070/
clinically negative CT + bone scan, PET/CT had SNS of 70% in MIBC
🧑🏻‍⚕️🤝👴🏽 #SharedDecision 4 cycles neoadju gem+cis