In issue 13:
Highlight on #FBXL4 E3 controlling basal mitophagy via NIX/#BNIP3 degradation
#Salicylic acid attenuates #brassinosteroid signaling by removing S-acylation from proteins
#Nucleoporin foci as stress-sensitive condensates
Mechanism of #botulinum #neurotoxin presynaptic targeting
Cover: Natalia Prevarskaya and coworkers
https://www.embopress.org/toc/14602075/2023/42/13

How do #botulinum toxins get to nerve ends to mediate #neurointoxication?
F. Meunier Lab shows that BoNT/A uptake into #synaptic #vesicles is via hijacking of a tripartite membrane nanocluster of #polysialogangliosides, #synaptotagmin and glycoprotein SV2
https://www.embopress.org/doi/10.15252/embj.2022112095

#JustPublished!
#ECDC's overview of recent cases of #botulism in Europe, linked to weight loss medical interventions performed in Türkiye.

Read more ⬇️⬇️⬇️
RT @ECDC_Outbreaks: #JustPublished!
#Botulism cases in Europe following medical interventions with #botulinum neurotoxin.

67 cases of botulism linked to intragastric injection of the botulism neurotoxin (#BoNT) have been reported in DE (12), AU (1), CH (1) & TR (53).

https://www.ecdc.europa.eu/en/news-events/botulism-cases-europe-following-medical-interventions-botulinum-neurotoxin

🐦🔗: https://n.respublicae.eu/ECDC_EU/status/1635653544773656577

[Automatic repost https://twitter.com/dystobot/status/1621479899197235201]

RT @ANA_journals: #GraphicalAbstracts DystoniaBoTXNet: Novel Neural Network #Biomarker of #Botulinum Toxin Efficacy in Isolated #Dystonia https://t.co/pqy6DOScog @TheNewANA1 @WileyNeuro @movedisorder https://t.co/kAe541xipR

A great article by a great doctor.
#Botulinum #DupuytrenContracture #collagenase #KeithDenkler https://www.clinicalcases.eu/index.php/acc/article/view/797/247