New @SciSignal experiments reveal how “sticking” to specific molecules facilitates the activation of #Tcells—potentially explaining how these immune cells are activated as they migrate into inflamed tissues. #CalciumSignaling https://scim.ag/3eB #press

New @SciSignal experiments reveal how “sticking” to specific molecules facilitates the activation of #Tcells—potentially explaining how these immune cells are activated as they migrate into inflamed tissues. #CalciumSignaling https://scim.ag/3bl #press

Grateful to the @dfg_public for funding this work at its outset through the TRR186 grant (to Peter Hegemann and me). #HUBerlin #CalciumSignaling #IonChannels

"To understand the basis for Ca2+ transport and signaling in Mtb, we determined Mtb’s transcriptional response to Ca2+. Overall, only few genes changed expression, suggesting a limited role of Ca2+ as a transcriptional regulator. However, 2 of the most strongly down-regulated genes were the pe15 and ppe20 genes that code for members of a large family of proteins that localize to the outer membrane and comprise many intrinsically disordered proteins."

#Tuberculosis #CalciumSignaling #PLOSBiology #Metabolism

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001906

Woohoo #AllThingsBrightAndCilia :blobcatwave: - we have the kick-ass Dagmar in the #Fediverse- @Wachtenlab huge welcome! Dagmar is queen of #Optigenetics #Biosensors #CalciumSignaling #Cilia #LiveImaging and well-worth having in your timeline!

Woohoo #AllThingsBrightAndCilia :blobcatwave: - we have the kick-ass Dagmar in the #Fediverse- @Wachtenlab huge welcome! Dagmar is queen of #Optigenetics #Biosensors #CalciumSignaling #Cilia #LiveImaging and well-worth having in your timeline!

Nested calcium dynamics support daily cell unity and diversity in the suprachiasmatic nuclei of free-behaving mice, according to a study. In PNAS Nexus: https://academic.oup.com/pnasnexus/article/1/3/pgac112/6639895 #CircadianRhythms #CalciumSignaling #Neurons