My Dresden colleagues have recently published a paper.
Carlotta Mayer (@c_ma_yer on the cross site) shows that #hepatocytes react to increased #bile #pressure by forming the #apical projections called bulkheads. This is also observed in #human #liver when bile pressure is increased to a pathological level. Upon further increase of bile pressure, bulkheads no longer hold the #canaliculi shape and form #rosettes.
#CellBiology #CellPolarity
https://doi.org/10.15252/embr.202357181
https://twitter.com/ZerialLab/status/1686028788658847744?s=20
#hepatocytes #bile #pressure #apical #human #liver #canaliculi #rosettes #cellbiology #cellpolarity
π¨Dancing Osteocytes!ππ»πΊπ»~90β95% of all cells in adult bone are #osteocytes interconnected by a vast network of #canaliculi. They play a key role in maintaining #bone health by sensing mechanical loading and orchestrating remodelling! π¦΄ππ¬
Read more: http://bit.ly/OsteocyteRCE