Hi #ScienceMastodon! Today's Research Highlight from JCS features work from Marijeta Kralj and colleagues at the Ruđer Bošković Institute and GENOS Glycoscience Research Laboratory in Croatia. In their paper, they explore why the drug salinomycin selectively targets cancer cells in epithelial-to-mesenchymal transition, a process associated with insidious cancer stem cells.
#CellBiology #cancerbio

Salinomycin hits EMT cancer cells where it hurts, at the Golgi
https://journals.biologists.com/jcs/article/136/17/e136_e1701/326604/Salinomycin-hits-EMT-cancer-cells-where-it-hurts

Fibroblast mitochondria fuel power-hungry cancer cells
https://journals.biologists.com/jcs/article/136/14/e136_e1403/324880/Fibroblast-mitochondria-fuel-power-hungry-cancer

Sharing the last Research Highlight for JCS Issue 14: Cynthia Reinhart-King and colleagues explore the relationship between invasive phenotypes in aggressive breast cancer cells and mitochondrial transfer from cancer-associated fibroblasts. Check out their findings on this 'metabolic symbiosis' that might drive tumor invasion.
#mitochondria #cancerbio #breastcancer

Hello all,

I moved instances and apparently lost my previous #introduction so I'm reposting.

I'm Kaylee, I'm a cancer neuroscience researcher and lab manager at Brigham and Women's Hospital in the lab of Dr. Humsa Venaktesh. We study how neurons and cancer cells interact both in the brain and elsewhere in the body.

#cancerbio #cancerbiology #neuro #neuroscience #cancerneuroscience #academia