MCBG Seminar 🧬 🧬 🧬

Thursday, September 14, 2023, 1 PM

Carly DeAntoneo, MCBG PhD Student

Advisor: Siddharth Balachandran, PhD
Fox Chase Cancer Center

Reovirus Z-NAs activate
ZBP1 dependent cell death

#GraduateSchool #GraduateStudents #GraduateStudies
#BiomedicalScience
#CancerBiology

ASAPbio Fellows Arpita Ghosh and Garima Jain are leading the Cancer Biology Crowd that has just completed its first #preprint review and posted it on PREreview!

Interested in #CancerBiology? Join the team!
https://prereview.org/reviews/8199664

Debasna Panigrahi, Sujit Bhutia identify MTP18 as a novel #mitophagy receptor and discover that MTP18-dependent mitophagy has implications in oral #cancer progression.
https://journals.biologists.com/jcs/article/136/13/jcs259986/323419/The-inner-mitochondrial-membrane-fission-protein

You can read more about this research in our ‘First person’ interview with Debasna Panigrahi: https://journals.biologists.com/jcs/article/136/13/jcs261435/323418/First-person-Debasna-Panigrahi

#cellbiology #cancerbiology #mitochondria

Receiving feedback on the #preprint is one of the most valuable features of posting #preprints.
If you have posted your manuscript as a preprint and want to receive feedback, we want to hear from you!
Categories of #research topic we are looking for:
🧪 Molecular and cellular #neurobiology
🧪 #CancerBiology
🧪 Computational #neuroscience:
🧪 Meta-research
🧪 #Metabolism

Please email jonny.coates@asapbio.org if you are interested.
https://buff.ly/3X0qAv7

The **Behind the paper** series at the #PLOSBiologue blog at #plosbiology @PLOSBiology is always inspiring and interesting. The newest is about findings in extramedullary hematopoiesis in tumors and tells about how Derek Barisas (MD/PhD student at WashU School of Medicine) nurtured the project through the pandemic—the lab shut down 3 months after he started.

https://biologue.plos.org/2023/07/05/tumors-produce-factors-that-promote-extramedullary-hematopoiesis/

Paper: https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001746

#cancerbiology
#behindthepaper
#scienceblogging

1/2

Have you posted a #preprint and would like to receive feedback?
We are calling on authors of preprints to submit their preprints to be reviewed by researchers as a part of the Crowd Preprint Review!
Categories of #research topic we are looking for:
🧪 Molecular and cellular #neurobiology
🧪 #CancerBiology
🧪 Computational #neuroscience:
🧪 Meta-research
🧪 #Metabolism
Details in https://asapbio.org/crowd-review-2023
If you would like to receive valuable feedback, please email jonny.coates@asapbio.org

#IDMastodon #Immunology #Cancerbiology #Drugdelivery @thelancet @ebiomedicine The #humanleukocyteantigen (HLA) is a highly polymorphic region, & HLA diversity may play a role in presenting tumour-associated peptides and inducing immune responses. understand the etiological role The role of HLA diversity on cancer development
📌 https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00153-6/fulltext
📌 https://www.thelancet.com/journals/ebiom/issue/current

How to use your neighbours to get ahead: #glioblastoma cells use #ExtracellularVesicles to encourage neighbouring #astrocytes to secrete pro-invasive #ECM components.

#preLight from Jade Chan covering work led by Dominik Koessinger #CRUK_BI

#CancerBiology

preLight: https://prelights.biologists.com/highlights/glioblastoma-extracellular-vesicles-influence-glial-cell-hyaluronic-acid-deposition-to-promote-invasiveness/

🧬MCBG Seminar🧬

Thursday, April 27, 1 PM

Teddy Nguyen
PhD student, Graduate Program in Molecular & Cell Biology & Genetics, Drexel University College of Medicine

Advisor: Dr. Erica Golemis
Fox Chase Cancer center

The role of Aurora Kinase A in modulating glycolysis in head and neck cancer

#CancerBiology #GraduateSchool

🧬MCBG Seminar🧬

Thursday, April 20, 1 PM

Flaviane Silva, PhD Student, MCBG Graduate Program, Drexel University College of Medicine

Advisor: Dr. Erica Golemis, Fox Chase Cancer Center

AURKA inhibition as a means of overcoming resistance to EGFR inhibitors in HNSCC

#CancerBiology #GraduateSchool

#Oncologyresearch #Cancerbiology #Molecularbiology understanding Molecular Mechanisms of #chemotherapy Resistance in Cancer Treatment
📌https://www.frontiersin.org/articles/10.3389/fonc.2021.640392/full
📌 https://www.frontiersin.org/subjects/chemotherapy-resistance
📌 https://www.frontiersin.org/journals/science/articles/10.3389/fsci.2023.997136?utm_source=fweb&utm_medium=nblog&utm_campaign=ba-sci-fsci-evolutionary-medicine-antibiotic-resistance-cancer-obsesity

🧬Drexel MCBG Dissertation Defense🧬

April 11, 3:00 pm, NCB 10-301

Alexa Cannon
Drexel MCBG Graduate Program

Advisor: Dr. Jonathan Chernoff
Fox Chase Cancer Center

Investigation of Novel Therapeutic Targets in RAC1-mutant Melanoma

#CancerBiology #CellBiology #GraduateSchool #GraduateStudies

Postdoctoral Position in Cancer Biology Research

https://jobrxiv.org/job/yale-university-27778-postdoctoral-position-in-cancer-biology-research/?feed_id=41508

#ScienceJobs #job #cancerresearch #postdoc #DNArepair #radiationoncology #therapeuticradiology #cancerbiology #cancer
New Haven #UnitedStatesUS #PostdoctoralFellow
https://jobrxiv.org/job/yale-university-27778-postdoctoral-position-in-cancer-biology-research/?feed_id=41508

@naturemedicine #Cancerbiology Both tumor immune infiltration and response to treatment are differentially associated with the subtype of #breastcancer according to the concordant or discordant character of the contralateral tumor. Pairs of tumors from different subtypes of breast cancers should be considered as singular entities before primary systemic treatment is considered, as observed responses might deviate from well-known profiles of response to #chemotherapy.

#Cancerbiology #oncologyresearch @naturemedicine Clinical, genomic and #transcriptomic analyses of paired samples of synchronous bilateral female #breastcancer identify associations between tumor concordance and #immune infiltrates levels and response to neoadjuvant treatment @FabienReyal @JoshWaterfall
📌 https://www.nature.com/articles/s41591-023-02216-8
📌 https://www.nature.com/nm/

The last presentation of our workshop on #reproducibility in #CancerBiology was by yours truly. I tried to discuss, from the point of view of the biologist doing lab experiments, what, to me, seem to be causes of unreliable research in the field, and what can be done to improve that.
Video: https://youtu.be/NOpp89m1omA
Because of technical issues the slideshow was not recorded on the video, so if you want to watch you may want to download the slideshow: https://www.dropbox.com/s/s1ahpc7ceamr66c/WorkshopReproducibility-GOMES_JE.pdf?dl=0

The fourth presentation of our workshop on #reproducibility in #CancerBiology was by Dawn Teare, from the University of Newcastle, discussing the use of #statistics in #biomedical #research

The talk can be viewed here: https://youtu.be/zvRSrxP3lsQ

The slideshow is available here: https://www.dropbox.com/s/93iscyckskiv4ks/020%20-%20TEARE%20DAWN%20-%20The%20implications%20of%20the%20use.pptx?dl=0

#OpenScience #CancerResearch #Cancer

Short thread👇

🧬Drexel MCBG Doctoral Dissertation Defense🧬

March 21, 2023, 1:00 pm

Konstantin Budagyan

Advisor: Dr. Jonathan Chernoff, Fox Chase Cancer Center

Exploring Allelic Differences in KRAS mutant CRC

#GraduateSchool #BiomedicalScience #PhD #CancerBiology #CellBiology #MolecularBiology

The third presentation of our workshop on #reproducibility in #CancerBiology was by Frédéric de Lamotte, from the INRAE in Montpellier, discussing #OpenScience, its challenges and how it relates to reproducibility in Biology.

The talk can be viewed here: https://youtu.be/0fP5ktMy5oY

The slideshow is available here: https://www.dropbox.com/s/o77a3nv3jpm4ymq/015%20-%20DE%20LAMOTTE%20-%20Open%20and%20reproducibility.pptx?dl=0
#OpenData #CancerResearch #Cancer
Short thread👇

The second talk on our workshop on #reproducibility in #CancerBiology was by Marcus Munafò, from the University of Bristol.
https://youtu.be/1xlhrgbushY
Slideshow available here: https://www.dropbox.com/s/kzk2f05c93ksbjk/010%20-%20Marcus%20Mufano.pptx?dl=0
Short thread👇
#OpenScience #Cancer #CancerResearch