New 📝 in @cellpress.mstdn.science #cancercell! Together with Valiente Lab we look at the electrophysiological signatures of 🧠 metastasis, using multi-electrode recordings and #MachineLearning . By Alberto Sanchez-Aguilera, Mariam Masmudi @acnavasolive & many others👉🏼 📝 https://www.sciencedirect.com/science/article/pii/S1535610823002507 👇🏼🧵

Very exciting that this paper is out now in #cancercell: https://www.cell.com/cancer-cell/fulltext/S1535-6108(23)00216-7

In brief: we show that in esophageal #adenocarcinoma #checkpoint #therapy success is predicted by an independent combination of mutation burden and the amount of #monocytes in the tumour pre-treatment (as measured by RNAseq). Very exciting link between #myeloid cells and #immune response to #cancer!

@epigenetics Hello! my lab is trying to find out why #epigenetic mechanisms evolve so rapidly in eukaryotes (and in #cancercell #evolution too). Everywhere we look there is diversity under the surface. Always looking for collaborations to investigate in far-flung corners of the tree of life!