#cardiomastodon EPA-based therapeutics appear to offer a major advance in #CVD risk reduction that adds to the protection afforded by #statins. REDUCE-IT demonstrated that high doses of a highly purified ethyl ester of EPA, icosapent ethyl, provided large relative and absolute risk reductions in #CVD mortality , #myocardialinfarction, #stroke, hospitalization for #unstableangina, and coronary revascularization in at-risk patients with triglycerides above ≈100 mg/dL despite therapy with statins…

#Cardiomastodon The aspirin-free strategy compared with the DAPT strategy failed to reduce major bleeding within 1 month after PCI, but it was non-inferior for the co-primary cardiovascular endpoint with a relative 50% margin. Aspirin used for a limited period of 1 month after PCI as part of DAPT might have provided protective effects on vulnerable coronary lesions, particularly in ACS patients, without significantly increasing major bleeding.

#cardiomastodon @nejm In patients with #heartfailure with preserved ejection fraction & #obesity, #semaglutide (2.4 mg) led to greater reductions in symptoms & physical limitations and greater improvements in exercise function than placebo. Full STEP-HFpEF #clinicaltrial
https://www.nejm.org/doi/pdf/10.1056/NEJMoa2306963?articleTools=true

#IDMastodon #CardioMastodon #LongCovid #covidheart
At 6-month follow-up, new-onset #persistenthypertension was seen in 20.6% of hospitalized patients with #COVID19 and 10.85% of nonhospitalized patients with #COVID19 . Incidence of new-onset persistent hypertension in patients with COVID-19 is higher than those with influenza . #SarsCoV2 may trigger new-onset #persistenthypertension In #PostCovid & #LongCovid
https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.123.21174

#Cardiomastodon Women are subject to gender inequality and inequity when it comes to their cardiovascular health. There are numerous reasons why this may be the case;
however, in 2023, this problem should not exist.
https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehad452/7235122?login=false

#cardiomastodon #Clinicaltrial #Delirium is common after #cardiacsurgery associated with adverse outcomes. #Benzodiazepine administration before /after cardiac surgery is associated with delirium; guidelines recommend minimizing their use. Benzodiazepine administration during cardiac surgery remains common because of recognized benefits.

#IDMastodon #cardiomastodon #COVIDheart Cardiovascular manifestations of #longCOVID inl stroke, chest pain, electrocardiographic abnormalities, postural tachycardia syndrome, atrial fibrillation, acute coronary syndrome,chronic thromboembolic pulmonary hypertension. A cohort of 153 760 infected individuals showed that #COVID19 patients are at ⏫️risk for & 1-year burden of incident CVDs, incl cerebrovascular disorders, arrhythmias, ischemic and nonischemic #CVD , thrombotic disorders.

#IDMastodon #cardiomastodon #Longcovid New onset of #hypertension was detected in 32.3% of patients at one-year follow-up #postCOVID19 recovery. Severe inflammation at the time of admission and severe CT severity score were associated with the development of new onset of hypertension on follow-up.
📌 https://www.sciencedirect.com/science/article/pii/S0019483223001037
📌 https://www.sciencedirect.com/journal/indian-heart-journal

#IDMastodon #cardiomastodon @eurekalert
NACMI: International #COVID19 Registry uncovers increased incidence of clotting in #heartattack patients with #COVID19 & #LongCovid
New analysis provides insights into #COVID19 impact on #coronaryarteries
📌https://www.eurekalert.org/news-releases/989893
📌 https://www.sciencedirect.com/science/article/pii/S0735109716333538
📌 https://www.bhf.org.uk/informationsupport/heart-matters-magazine/news/coronavirus-and-your-health/long-covid

#Cardiomastodon #loopdiuretics cause measurable decreases in BV within hours of a single dose. Single doses of loop diuretics produce measurable changes in relative blood volume that follow distinct profiles for subjects with & without congestive #heartfailure When measured alongside urine output, these profiles may be used to estimate plasma refill rates — potential patient-specific targets for decongestive therapy across serial diuretic doses @CJCJournals

#Cardiomastodon @medflutter_ Cardio Pocket Diary🫀

#Cardiomastodon #ICU in this #Clinicalinvestigation Elevated hs-cTnT in patients seeking care for chest pain in absence of #MyocardialInfarction showing that high hs-cTnT values can mirror myocardial injury in other types of myocardial injuries than MI
📌 https://bmcemergmed.biomedcentral.com/articles/10.1186/s12873-023-00787-w#Fig2
📌 https://bmcemergmed.biomedcentral.com/articles

#cardiomastodon @bmj_latest
The right dietary & lifestyle would minimised the mortality risks in diabetes individuals. In this #cohortstudy of 15 486 patients in the course of 18.5 years of followup .Higher intake of SSBs was associated with higher all cause mortality & #CVD incidence & mortality, whereas intakes of coffee, tea, plain water, and low fat milk were inversely associated with all cause mortality incase of #T2D individual
https://www.bmj.com/content/381/bmj-2022-073406

#IDMastodon #cardiomastodon #Longcovid /#COVID19 @biomedcentral
the effect of chronic use of RAAS blockers, as in case of treatment of cardiovascular diseases , on the expression of ACE2 & the implications of these differences in cohorts with ACE2 levels and #COVID19 outcomes.
📌 https://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/s40360-023-00667-w
📌 https://bmcpharmacoltoxicol.biomedcentral.com

#Neurobiology #Cardiomastodon #Neuroimmunology #Schizophrenia - One Name, Many Different Manifestations
📌 https://www.sciencedirect.com/science/article/pii/S2215036622004035
📌 https://www.sciencedirect.com/science/article/abs/pii/S0306987723000555?via%3Dihub
📌 https://www.sciencedirect.com/science/article/abs/pii/S0920996421004539
📌https://www.nature.com/articles/s41380-023-01949-9
📌 https://www.sciencedirect.com/science/article/abs/pii/S0920996422004601

@jama_current #Cardiomastodon Lack of Benefit of Renin-Angiotensin System Inhibitors in #COVID19
📌 https://jamanetwork.com/journals/jama/fullarticle/2803540
📌 https://jamanetwork.com/journals/jamacardiology/fullarticle/2765049

#IDMastodon #cardiomastodon @NIAIDNews A daily statin was found to reduce the risk of #CVD in people living with #HIV
📌 https://www.niaid.nih.gov/news-events/daily-statin-reduces-risk-cardiovascular-disease-people-living-hiv-large-nih-study?utm_medium=social&utm_source=twitter&utm_campaign=news_reprieve_news_events_4112023

#cancerresearch @nature #Cardiomastodon
Understanding the common mechanisms of heart & Pathological alterations underlying skeletal muscle wasting in #cancercachexia.
📌https://www.nature.com/articles/s41389-020-00288-6
📌 https://www.nature.com/oncsis/

#IDmastodon #Cardiomastodon α1-Adrenergic Receptors: Insights into Potential Therapeutic Opportunities for #COVID19, #HeartFailure, and #alzheimersdisease
📌 https://www.mdpi.com/1422-0067/24/4/4188
📌 https://www.mdpi.com/journal/ijms/special_issues/25601NF5N0

#publichealth @bmj_latest #Cardiomastodon Moderate certainty evidence shows that programmes promoting Mediterranean and low fat diets, with or without physical activity or other interventions, reduce all cause mortality and non-fatal #MyocardialInfarction in patients with increased cardiovascular risk. M program are also likely to reduce stroke risk.Generally, other named dietary programmes were not superior to minimal intervention.
https://www.bmj.com/content/380/bmj-2022-072003