WhatisBiotechnology · @WhatisBiotechnology
98 followers · 589 posts · Server mstdn.science
On this day in 2005: CRISPR noted to provide immunity and degrade DNA as means to prevent infection #CRISPR #Cas9 #ThisDayInBiotech
#crispr #cas9 #thisdayinbiotech
CellBioNews · @cellbionews
78 followers · 1629 posts · Server scientificnetwork.de
#Mosquito-friendly #gene_drive may lead to a #malaria-free future.
https://phys.org/news/2023-07-mosquito-friendly-gene-malaria-free-future.html
#mosquito #gene_drive #malaria #cas9 #RNA
TrangAston :verified: · @CastlTrAstonDrs
1337 followers · 2688 posts · Server med-mastodon.com
#IDMastodon #viralimmunology #CellImmunity Understanding protective immunity to #COVID19 facilitates preparedness for future pandemics & combats new #SARSCoV2 variants emerging in the human population & phospholipid scramblase 1 (PLSCR1) as a potent cell-autonomous restriction factor against live #SARSCoV2 infection in parallel #genome-wide #CRISPR–#Cas9 screens of human lung epithelia & hepatocytes . before and after stimulation with IFNγ.
#IDMastodon #viralimmunology #cellimmunity #COVID19 #SarsCoV2 #genome #crispr #cas9
ISOGG · @isogg
292 followers · 58 posts · Server genealysis.socialNew nanoparticles can perform gene editing in the lungs
Using these RNA-delivery particles, researchers hope to develop new treatments for cystic fibrosis and other lung diseases. #dna #CRISPR #RNA #geneediting #nanoparticles #isogg #cas9 #geneadons #epigenetics
https://news.mit.edu/2023/new-nanoparticles-can-perform-gene-editing-lungs-0330
#dna #crispr #rna #geneediting #nanoparticles #isogg #cas9 #geneadons #epigenetics
Biologic Models · @biologicmodels
11 followers · 58 posts · Server mstdn.science
#CRISPR #Cas9 is an #RNA-guided #DNA endonuclease. Cas9 cleaves double-stranded DNA targets with a protospacer adjacent motif (PAM), which is the compliment to the guide RNA. Explore the x-ray crystallography structure #3DPrint https://biologicmodels.com/pdb/5axw/crispr-cas9/
#crispr #cas9 #RNA #DNA #3dprint
Admin Córdoba de León · @AdminCordoba
71 followers · 348 posts · Server mstdn.science
RT @0000_2104
Happy to share a new preprint! Using #CRISPR #Cas9 we obtained a large fitness landscape of DHFR in E. coli (260,000 genotypes). This landscape shows unexpected properties. It is rugged and yet highly accessible for evolution (1/n). Link: https://www.biorxiv.org/content/10.1101/2023.02.27.530293v1
yeti · @yeti
75 followers · 158 posts · Server emacs.chScience & Cocktails
Genetically modifying everything with John van der Oost
https://www.youtube.com/watch?v=drR9GnFZ1C4
#ScienceAndCocktails #JohnVanDerOost #aminoAcid #Cas9 #Cas12 #CRISPRCas #crRNA #DNA #gene #mRNA #protein #replication #RNA #tRNA
#scienceandcocktails #johnvanderoost #aminoacid #cas9 #cas12 #crisprcas #crrna #dna #gene #mrna #protein #replication #rna #trna
Biologic Models · @biologicmodels
11 followers · 58 posts · Server mstdn.science
#CRISPR #Cas9 is an #RNA-guided #DNA endonuclease. Cas9 cleaves double-stranded DNA targets with a protospacer adjacent motif (PAM), which is the compliment to the guide RNA. Explore the x-ray crystallography structure #3DPrint https://biologicmodels.com/pdb/5axw/crispr-cas9/
#crispr #cas9 #RNA #DNA #3dprint
Laborjournal · @laborjournal
521 followers · 241 posts · Server mstdn.science
Nicht selten wirken pathogene #Mutationen über die Verschiebung des Leserasters in einem #Protein-codierenden #Gen. Auf welche Weise Frame-Editoren aus Polymerase und #Cas9-Nuklease sie künftig korrigieren könnten, beschreibt @MBozukova@twitter.com: 👉 https://www.laborjournal.de/editorials/2664.php
Vivek Mutalik · @vivek_mutalik
493 followers · 400 posts · Server fediscience.org
Compact Cas9d and HEARO enzymes for genome editing discovered from uncultivated microbes
#genetictools #synbio #biotech #GenomeEditing #crispr #cas9
Vivek Mutalik · @vivek_mutalik
452 followers · 305 posts · Server fediscience.org
#Polarity of the #CRISPR roadblock to #transcription | Nature Structural & Molecular Biology
#cas9 #cas #genetictools #transcription #crispr #polarity
Vivek Mutalik · @vivek_mutalik
405 followers · 198 posts · Server fediscience.orgImproved bacterial single-cell RNA-seq through automated MATQ-seq and Cas9-based removal of rRNA reads | bioRxiv
#SingleCell #crispr #cas9 #rnaseq
PLOS Biology · @PLOSBiology
3246 followers · 272 posts · Server fediscience.org
Target site preferences mean that no single #Cas9 can edit all sequences. Study identifies PI domain variants in natural SaCas9 orthologs that recognize a simple NNGG PAM; these can confer NNGG PAM recognition, expanding the #CRISPR repertoire #PLOSBiology https://plos.io/3gJB4OR
PLOS Biology · @PLOSBiology
3244 followers · 269 posts · Server fediscience.org
Target site preferences mean that no single #Cas9 can edit all sequences. Study identifies PI domain variants in natural SaCas9 orthologs that recognize a simple NNGG PAM; these can confer NNGG PAM recognition, expanding the #CRISPR repertoire #PLOSBiology https://plos.io/3gJB4OR
PLOS Biology · @PLOSBiology
3234 followers · 256 posts · Server fediscience.org
Target site preferences mean that no single #Cas9 can edit all sequences. Study identifies PI domain variants in natural SaCas9 orthologs that recognize a simple NNGG PAM; these can confer NNGG PAM recognition, expanding the #CRISPR repertoire #PLOSBiology https://plos.io/3gJB4OR
Lars Barquist · @lbarquist
222 followers · 73 posts · Server mstdn.science
Our new #bacterial #scRNAseq preprint is out, building on the Vogel lab's MATQ-seq approach. We automate to increase cell numbers, increase sensitivity, and deplete rRNA using #Cas9, before applying this to gene expression heterogeneity along the #Salmonella growth curve.
#bacterial #scrnaseq #cas9 #Salmonella
I choose to be anonymous cowar · @Hello57
34 followers · 443 posts · Server noc.socialFor those of you who are not at a PhD/biology level of knowledge, the CRISPR Cas9 field is still exploding with amazing new ideas
https://twitter.com/omarabudayyeh/status/1595872561178578946
sadly paywalled
Julien M. · @julm
485 followers · 4935 posts · Server framapiaf.org#Biologie #AFIS #Science
> Et l'homme créa les #plantes (pour mieux se #nourrir)
> Avec #FrançoisParcy, Directeur de Recherche au #CNRS au Laboratoire de #physiologie cellulaire et végétale de #Grenoble.
> 05:00 : Quizz sur l'#origine des plantes
> 11:42 : Des tas de changements
> 13:21 : La #détoxification
> 21:14 : Le #maïs et son ancêtre
> 31:24 : La #domestication
> 36:29 : L'#hybridation et la #mutagenèse
> 37:29 : La #transgenèse
> 39:33 : #CRISPR-#CAS9
https://youtube.com/watch?v=zE1WrrgUgYg
#cas9 #crispr #transgenèse #mutagenèse #hybridation #domestication #maïs #détoxification #origine #grenoble #physiologie #cnrs #FrançoisParcy #nourrir #plantes #science #afis #biologie
Grégory PAUL · @paulgreg
130 followers · 1646 posts · Server framapiaf.orgMail-Order CRISPR Kits Allow Absolutely Anyone to Hack DNA https://www.scientificamerican.com/article/mail-order-crispr-kits-allow-absolutely-anyone-to-hack-dna/?wt.mc=SA_Twitter-Share via @sciam #CRISPR #cas9 #biology