Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology https://plos.io/3p6klcm
#plosbiology #caspase #gsdme #Amphioxus #pyroptosis #Gasdermin
Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology https://plos.io/3p6klcm
#plosbiology #caspase #gsdme #Amphioxus #pyroptosis #Gasdermin
Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology https://plos.io/3p6klcm
#plosbiology #caspase #gsdme #Amphioxus #pyroptosis #Gasdermin
Pathogen hijacks programmed cell death signaling by arginine ADPR-deacylization of caspases
https://www.sciencedirect.com/science/article/pii/S1097276522002192
#t3ss #bacteria #signaling #caspase #pathogen
The findings of this study open up possibilities for further research on the role of ATP in apoptosis, as well as potential therapeutic targets for controlling cell death.
#ATP #Cell #CellDeath #Apoptosis #Caspase-3 #Pannexin-1 #Metabolism #FRET #Biosensors
#atp #cell #CellDeath #apoptosis #caspase #pannexin #metabolism #fret #biosensors