@mrbatsu

CCL11 (aka eotaxin-1) has been found to be elevated in ppl w/ Long Covid cognitive symptoms [1] & this could contribute to neuroinflammation.

Montelukast lowers CCL11 & research on repurposing for Alzheimer's is underway [2]. However, montelukast use has been linked to increased suicidal ideation.

Does anyone know why it would increase suicidal ideation?

1 - https://doi.org/10.1101/2022.01.07.475453
2 - https://clinicaltrials.gov/ct2/show/NCT03991988

#montelukast #neuroinflammation #CCL11