Hi #ScienceMastodon! Check out the last Research Highlight from Issue 17 of JCS: Ke Hu and colleagues at Arizona State University mess with microtubule-associated proteins in Toxoplasma gondii to answer whether the distinct helical motility of this apicomplexan parasite arises from the spiral arrangement of its remarkably stable cortical microtubules.
#CellBiology #microtubules #parasitology

Function follows form of cortical microtubules in Toxoplasma gondii
https://journals.biologists.com/jcs/article/136/17/e136_e1702/327904/Function-follows-form-of-cortical-microtubules-in

'Using mammalian cells in culture, we discovered that they adapt to chronic mild stresses of up to two weeks, notably proteotoxic stresses such as heat, by increasing their size and translation, thereby scaling the amount of total protein.'

#Preprint #CellBiology

https://www.biorxiv.org/content/10.1101/2023.01.25.525547v3

Xinyi Huang, Yaming Jiu and colleagues find a positive correlation between host cell contractility and Zika virus infection efficacy.
https://journals.biologists.com/jcs/article/136/17/jcs261301/328138/Actomyosin-dependent-cell-contractility
#zika #virology #cellbiology

Chris Stefan at #LMCB #UCL is looking for a postdoc to study membrane organisation in hepatocyte and epithelial cell architecture. #CellBiology

https://www.ucl.ac.uk/work-at-ucl/search-ucl-jobs/details?jobId=14681&jobTitle=Postdoctoral+Research+Fellow

I'm thrilled to have been a small part of an amazing team to work on uncovering how plants regulate lateral root angles using auxin, PIN auxin transporters, and phosphorylation status. #auxin #phosphorylation #cellbiology #gravitropism https://www.nature.com/articles/s41477-023-01478-x

Hi #ScienceMastodon! Today's Research Highlight from JCS features work from Marijeta Kralj and colleagues at the Ruđer Bošković Institute and GENOS Glycoscience Research Laboratory in Croatia. In their paper, they explore why the drug salinomycin selectively targets cancer cells in epithelial-to-mesenchymal transition, a process associated with insidious cancer stem cells.
#CellBiology #cancerbio

Salinomycin hits EMT cancer cells where it hurts, at the Golgi
https://journals.biologists.com/jcs/article/136/17/e136_e1701/326604/Salinomycin-hits-EMT-cancer-cells-where-it-hurts

Our lab (Toyooka Lab @LabToyooka) at Drexel University in Philadelphia is seeking a research assistant who is enthusiastic about autism research. We study the efficacy of peptides on neuronal morphology (neurite/spine/synapse formation), neural circuits and behaviors using autism mouse models (See the details about the project at the lab webpage: https://toyooka-lab.academic.ws/).

Please see the details and apply for this position (Job #: 501807) at the Drexel Human Resources website. https://careers.drexel.edu/en-us/job/501807/research-assistant-i

If you have any questions, please email me at kt469@drexel.edu.
#autism #ASD #therapy #DrugDiscovery #ResearchAssistant #ResearchAssistantJob #AcademicJob #LabTechnician #neuroscience #brain #CellBiology #BrainDevelopment #neurodevelopment #neurodevelopmentalDisorder #Axon #dendrites #Synapse #NeuralCircuit #philadelphia

Our lab (Toyooka Lab @LabToyooka) at Drexel University in Philadelphia is seeking a postdoctoral researcher who is enthusiastic about autism research. We study the efficacy of peptides on neuronal morphology (neurite/spine/synapse formation), neural circuits and behaviors using autism mouse models (See the details about the project at the lab webpage: https://toyooka-lab.academic.ws/).

Please see the details and apply for this position (Job #: 501741) at the Drexel Human Resources website. https://careers.drexel.edu/en-us/job/501741/postdoctoral-researcher

If you have any questions, please email me at kt469@drexel.edu.

#autism #ASD #therapy #DrugDiscovery #postdoc #PostdocJob #AcademicJob #neuroscience #brain #CellBiology #BrainDevelopment #neurodevelopment #neurodevelopmentalDisorder #Axon #dendrites #Synapse #NeuralCircuit #philadelphia

For the first day of #SciArtSeptember, I thought I'd share one of my most tasty projects: Cell Biology candy.

I can't help but smile, still, when I remember it.

#SciArt #CellBiology #art #MastoArt

Riley Cooney, Eszter Vladar and colleagues discover that DKK3 and WNT4 work together to enable a switch from canonical to non-canonical Wnt signalling during multiciliogenesis.

https://journals.biologists.com/jcs/article/136/16/jcs260807/326574/A-WNT4-and-DKK3-driven-canonical-to-noncanonical

#cellbiology #wnt #signalling #electronmicroscopy

Tomorrow, the Rockin' Science Tour by Miltenyi Biotec will make a stop at the Leibniz-HKI 🚛

From 11 a.m. to 4 p.m, talk to experts about cell culture🧫, flow cytometry and more🦠🔬!

Or just stop by during your lunch break to play a few games and win some prizes🎈

#ScienceFestival #Science #microbiology #microscopy #cellbiology #cellculture

For the latest Research Highlight from JCS, we have a Short Report from Kenta Terai and colleagues at Kyoto University and the RIKEN Center for Brain Science in Japan. Using a series of Madin–Darby canine kidney (MDCK) cell lines with single and combined knockouts of the four ErbB receptors, the authors dissect roles of each receptor in complex epithelial cell behaviors. Learn more here: How ErbB receptors keep epithelial tissues in shape
https://journals.biologists.com/jcs/article/136/16/e136_e1603/325950/How-ErbB-receptors-keep-epithelial-tissues-in

#CellBiology #ScienceMastodon

This looks cool from the Borner Lab. Improved dynamic organellar maps (proteomic method for looking at protein abundance/location) with the same mass spec time.

https://www.nature.com/articles/s41467-023-41000-7

#Proteomics #CellBiology

Cell Press社区评论的首席编辑Sejal Vyas博士正在圣地亚哥参加Cell Symposia。如果您也在场，请预约面谈时间与Sejal 讨论您的研究！#cellsymposia #cellpress #science #biology #CellBiology. 🔗在网站未公开之前，无法查看其内容或下载可能产生的文件。 请您谅解。是否我还能为您提供其他方面的帮助呢？

My Dresden colleagues have recently published a paper.

Carlotta Mayer (@c_ma_yer on the cross site) shows that #hepatocytes react to increased #bile #pressure by forming the #apical projections called bulkheads. This is also observed in #human #liver when bile pressure is increased to a pathological level. Upon further increase of bile pressure, bulkheads no longer hold the #canaliculi shape and form #rosettes.
#CellBiology #CellPolarity

https://doi.org/10.15252/embr.202357181

https://twitter.com/ZerialLab/status/1686028788658847744?s=20

Interesting work from the labs of David Baker and Carolyn Bertozzi showing EndoTag proteins, designed to bind extracellular face of receptors, target complexes for degradation.

Designed Endocytosis-Triggering Proteins mediate Targeted Degradation and amplify signaling
https://www.biorxiv.org/content/10.1101/2023.08.19.553321v1

#CellBiology #MembraneTrafficking

Kimiya Matsuda, Kenta Terai and colleagues dissect the role of ErbB genes in proliferation, survival and collective cell migration via systematic knockouts.
Highlight: https://journals.biologists.com/jcs/article/136/16/e136_e1603/325950/How-ErbB-receptors-keep-epithelial-tissues-in
Article: https://journals.biologists.com/jcs/article/136/16/jcs261199/325936/Knockout-of-all-ErbB-family-genes-delineates-their
#CellBiology #cellmigration

Happy Monday again, #ScienceMastodon! The first Research Highlight from JCS Issue 16 features a paper from Toshiyuki Oda and colleagues at the Universities of Yamanashi and Tokyo, using the unicellular algae Chlamydomonas reinhardtii to break down roles of tubulin modifications in ciliary/flagellar motility. #CellBiology #microtubules #flagellates

Roles of ciliary tubulin PTMs in Chlamydomonas reinhardtii
https://journals.biologists.com/jcs/article/136/16/e136_e1601/325932/Roles-of-ciliary-tubulin-PTMs-in-Chlamydomonas

Looking for old friends and new in the field of #rarediseases #cellbiology #redox #medicine #science. Still kind of #newhere

‘To help make connections: name 5–7 things that interest you but aren’t in your profile, as tags so they are searchable. Then boost this post or repeat its instructions so others know to do the same.’

OK, I’ll try to choose things that aren’t in *any* of my fediverse profiles! Hmm 🤔

How about #biology, #HumanComputerInteraction, #learning, #mindfulness, #philosophy, #psychology and #UrbanDesign for starters?

Relatedly:
#accessibility #ActiveTravel #aphantasia #AutobiographicalMemory #biochemistry #BodyDoubling #CellBiology #ColourPerception #consciousness #genetics #GreenSpace #HCI #hearing #hyperphantasia #mind #neuroscience #perception #SDAM #SoftwareDesign #TransitSystems #UrbanTransit #UserExperience #vision