#Phosphorylation control in #mitosis:
Julie Welburn and colleagues reveal the molecular basis for #cellcycle regulation of #Kif4A and #CENPE motor interaction with #PRC1, needed to organize antiparallel #microtubule bundles and to ensure central spindle integrity, #midbody assembly and #cytokinesis
#phosphorylation #Mitosis #cellcycle #kif4a #cenpe #prc1 #microtubule #midbody #cytokinesis
⏳Oportunidad de #trabajo en #ciencia. Colegas de #Argentina llaman a cubrir un #postdoc para reparación del #ADN, #ciclocelular, y estabilida del #genoma.
#jobsinstem ➡️ Argentinean colleagues have an open call for #Postdocs in #dnarepair, #cellcycle regulation and #genome stability.
#biologia #proteinas #molecular #Mendoza #biology #CABA #genome #DNA #genomics #molecularbiology #proteins #biochemistry #conicet
#conicet #biochemistry #proteins #molecularbiology #genomics #dna #caba #biology #mendoza #molecular #proteinas #biologia #genome #cellcycle #dnarepair #Postdocs #jobsinstem #genoma #ciclocelular #adn #postdoc #argentina #ciencia #trabajo
A #transcription-independent mechanism -#RBM10-mediated RNA alternative #splicing coupled to nonsense-mediated #mRNA decay- determines rapid periodic fluctuations of #BRCA1 expression throughout the #cellcycle
#transcription #rbm10 #splicing #mrna #brca1 #cellcycle
"In this study, we revisit and significantly extend the initiator-titration model, proposed thirty years ago, and explain how bacteria precisely and robustly control replication initiation based on the mechanism of protein copy-number sensing."
#preprint #microbiology #cellcycle
Transferred #mitochondria accumulate reactive oxygen species, promoting proliferation. #Cancer #ReactiveOxygenSpecies #CellCycle https://elifesciences.org/articles/85494?utm_source=mastodon&utm_medium=social&utm_campaign=organic
#cellcycle #reactiveoxygenspecies #cancer #mitochondria
Very interesting work with implications beyond #metabolism / #biosynthesis and cell cycle in #yeast.
https://www.nature.com/articles/s42255-023-00741-x
#Microbiology #CellCycle #Proteins #Carbohydrates #Lipids
#Lipids #carbohydrates #proteins #cellcycle #microbiology #yeast #biosynthesis #metabolism
How is #biomass production controlled during cell growth and the cell cycle?
New assay by Clovis Basier & Paul Nurse @thecrick using unperturbed exponentially growing populations shows how #cellcycle and cell size affect global rates of RNA and protein synthesis in #fissionyeast
#RefereedPreprint c/o @ReviewCommons now published in revised form!
#biomass #cellcycle #fissionyeast #refereedpreprint
#Cells avoid #multitasking: Examining the cause of #metabolic oscillations that lead up to cell #division.
https://phys.org/news/2023-02-cells-multitasking-metabolic-oscillations-cell.html
#cells #multitasking #metabolic #division #mitosis #cellcycle
The molecular basis for recognition of #CENPA #nucleosomes by ‘Mis18 licensing factor component #KNL2:
Tatsuo Fukagawa and coworkers present #cryoEM structure with chicken KNL2 and insight into its dynamic localization regulation during the #cellcycle
https://www.embopress.org/doi/10.15252/embj.2022111965
#cenpa #nucleosomes #knl2 #cryoem #cellcycle
And in case you missed it:
Before Christmas we published that different signalling signatures can drive S-phase acceleration during regeneration.
#regeneration #drosophila #stresssignalling #cellcycle #sphase
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010516
#regeneration #drosophila #stresssignalling #cellcycle #sphase
Scientists discover ch-TOG #protein is essential for building and maintaining the #cell skeleton
#cytoskeleton #ch_TOG #cellcycle
https://phys.org/news/2023-01-scientists-ch-tog-protein-essential-cell.html
#protein #cell #cytoskeleton #ch_tog #cellcycle
Take a look at our 'First person' interview with Leeba Ann Chacko on her PhD project in the lab of Vaishnavi Ananthanarayanan at the Single Molecule Science initiative, University of New South Wales, Sydney, Australia, investigating how mitochondrial volume homeostasis is maintained during the cell cycle: https://journals.biologists.com/jcs/article/136/1/jcs260895/286575/First-person-Leeba-Ann-Chacko
#cellbiology #research #cellcycle #microtubules #mitochondria
#cellbiology #research #cellcycle #microtubules #mitochondria
Cover feature in issue 42/2:
#Golgi #oxygen sensor controlling #intestinal ‘mucin #glycosylation
by Tal Ilani, Deborah Fass and colleagues with SciStories.com
And:
Gut colonization via #GTPase-less EF-G paralog
#Yeast cells in two minds about #cellcycle start
#MASTL/#PP2A module restraining #PI3K-Akt
Zinc-dependent structural transition in ALS-mutated #SOD1
https://www.embopress.org/toc/14602075/2023/42/2
#golgi #oxygen #intestinal #glycosylation #gtpase #yeast #cellcycle #mastl #pi3k #sod1
replicationists (eukaryotes dept.) take note 👇
(thx for the shoutout @Speck_Lab)
https://www.sciencedirect.com/science/article/pii/S1097276522012035
https://twitter.com/STCmicrobeblog/status/1614597627550523392?t=VQ8Tb7eP13Yo0l8uGStyXQ&s=19
#replication #cellcycle #microbiology
cell cyclists & divisionists take note 👇
The cell cycle of Staphylococcus aureus: An updated review
Maria D. Barbuti, Ine S. Myrbråten, Danae Morales Angeles, Morten Kjos
@vscooper this is an important paper, no question. and a beautiful and much needed demonstration why&where 'averaging' of cells doesn't really lead to a better understanding of cell cycle regulation.
#cellcycle #microbiology
The thread I re-tooted just now from @redrockcity is absolutely worth your time, as well as the paper:
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010505
#microbiology #division #replication #cellcycle
cell divisionists (E. coli & Co.) take note 👇
(first) great 🧵of petra levin (@Redrockcity) on mastodon, yay!
https://mstdn.science/@Redrockcity/109648766874888003
#microbiology #CellDivision #cellcycle #replication
p.s. also the Caulo·philes might profit from reading 🤗 @BrunlabCaulo @goleylab & friends
#microbiology #CellDivision #cellcycle #replication
Krystal Timón Pérez, Jacopo Scrofani and Isabelle Vernos show that #phosphorylation of #NEDD1 at S411 is essential for the coordination of #microtubule nucleation during #mitosis:
https://journals.biologists.com/bio/article/11/11/bio059474/282931
#CellScience #CellCycle #Biology #Science #AcademicMastodon #BiologyOpen
#phosphorylation #nedd1 #microtubule #mitosis #cellscience #cellcycle #biology #Science #AcademicMastodon #biologyopen
In this Research Article, Marjan Abbasi et al. identify two #phosphosites in the #yeast spindle pole body protein Spc110 that regulate timely cell cycle progression:
https://journals.biologists.com/bio/article/11/11/bio059565/280976
Find out more about the story behind the paper in this interview with first author Marjan, who is a PhD student in the lab of Victoria Menendez-Benito at the Karolinska Institutet, Stockholm, Sweden:
https://journals.biologists.com/bio/article/11/11/bio059713/281165
#Centrosome #SPB #CellScience #Biology #Science #CellCycle #Research #BiologyOpen
#phosphosites #yeast #centrosome #spb #cellscience #biology #Science #cellcycle #research #biologyopen