Scientists have captured the most detailed images of cell division ever using a new microscopy technique. The technique, called lattice light-sheet microscopy, allows them to observe the movements and interactions of molecules inside living cells in 3D and real-time. It could reveal new insights into the mechanisms and regulation of cell division and the causes and consequences of errors that lead to diseases such as cancer.

#CellDivision #Microscopy #Molecules

https://www.sciencealert.com/we-just-got-an-unprecedented-look-at-the-details-of-cell-division?utm_source=flipboard&utm_content=HariTulsidas%2Fmagazine%2FMind+and+Matter

James Glover, Edward Scourfield, Monica Agromayor, Juan Martin-Serrano and colleagues identify UMAD1 as a novel component of the ESCRT machinery that facilitates cytokinetic abscission.
Highlight: https://journals.biologists.com/jcs/article/136/15/e136_e1503/325852/UMAD1-helps-ESCRT-machinery-sever-ties-during
Article: https://journals.biologists.com/jcs/article/136/15/jcs261097/325840/UMAD1-contributes-to-ESCRT-III-dynamic-subunit
#OpenAccess

Read more about this research in the ‘First person’ interview with James Glover: https://journals.biologists.com/jcs/article/136/15/jcs261498/325841/First-person-James-Glover

#CellBiology #celldivision

Referenced link: https://phys.org/news/2023-06-weight-team-protein-key-chromosome.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-06-weight-team-protein-key-chromosome.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1666822410858020871#m

Pulling its weight: Team identifies #protein key to chromosome movement during #celldivision @osaka_univ @MolecularCell https://linkinghub.elsevier.com/retrieve/pii/S1097276523003799 https://phys.org/news/2023-06-weight-team-protein-key-chromosome.html

Referenced link: https://phys.org/news/2023-05-understudied-cell-division-nanomachine-revealed.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-05-understudied-cell-division-nanomachine-revealed.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1663938285670989827#m

Detailed structure of understudied #celldivision 'nanomachine' revealed @icrnews https://www.nature.com/articles/s41467-023-38276-0 https://phys.org/news/2023-05-understudied-cell-division-nanomachine-revealed.html

Referenced link: https://phys.org/news/2023-04-id-protein-cancer-cells-cell.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-04-id-protein-cancer-cells-cell.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1650851166182334465#m

Researchers ID protein that helps #cancercells in #celldivision process @MUSCHealth https://www.nature.com/articles/s41418-023-01140-1 https://phys.org/news/2023-04-id-protein-cancer-cells-cell.html

#Celldivision protein FtsK coordinates bacterial #chromosome segregation and daughter cell separation in #Staphylococcus #aureus
Helena Veiga, Mariana Pinho et al show #FtsK interacts with the #chaperone #Triggerfactor and establishes its gradient towards the #septum to promote stability and export of the #peptidoglycan #hydrolase Sle1.

https://www.embopress.org/doi/10.15252/embj.2022112140

Referenced link: https://phys.org/news/2023-03-mechanism-dna-segregation-cell-division.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-03-mechanism-dna-segregation-cell-division.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1631311414479532035#m

Researchers find mechanism that ensures correct #DNA segregation in #celldivision @hkuniversity @CellReports https://linkinghub.elsevier.com/retrieve/pii/S2211124723000438 https://phys.org/news/2023-03-mechanism-dna-segregation-cell-division.html

Referenced link: https://phys.org/news/2023-02-cells-multitasking-metabolic-oscillations-cell.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-02-cells-multitasking-metabolic-oscillations-cell.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1630236328808857601#m

#Cells avoid multitasking: Examining the cause of metabolic oscillations that lead up to #celldivision @univgroningen https://phys.org/news/2023-02-cells-multitasking-metabolic-oscillations-cell.html

#celldivision

A fly library of fluorescently labeled RhoGEF/GAP to unveil molecular mechanisms of de novo junction formation and neighbor response upon cell division.
#Drosophila #development #biology #CellDivision #MechanoBiology #MechanoSensing
https://www.cell.com/current-biology/fulltext/S0960-9822(23)00062-3

#Celldivision is fundamental to life, but still not fully understood.

@SPOREMOHAN & his team @warwickuni take a closer look at the the complex ring of #proteins that guide the process.

Read more 👉 https://bit.ly/3YkSgv3

#microscopy #biochemistry #biomolecules #genetics

🐦🔗: https://n.respublicae.eu/ERC_Research/status/1604068922512539648

Gracias #cepave_conicet ,por dar difusión a esta publicación científica
#meiosis #genetica #Chromosome

Cita completa: Sergio Gustavo Rodríguez Gil, Maia Fradkin & América Nitxin Castañeda-Sortibrán @nitxin (2018): Conceptions of meiosis: misunderstandings among university students and errors, Journal of Biological Education, DOI: 10.1080/00219266.2018.1469531
Link del trabajo: https://doi.org/10.1080/00219266.2018.1469531

#meiosis #educacion #cromosoma #chromosome #celldivision #genetics #cytogenetics

"[...] a tension-dependent signal on the #nucleus that sets the time for nuclear envelope permeabilization (NEP) and mitotic entry. This signal relies on #actomyosin #contractility, which unfolds the nucleus during the G2-M transition, activating the stretch-sensitive #cPLA2 on the nuclear envelope and regulating the nuclear translocation of #cyclin B1.[...]"
https://rupress.org/jcb/article-abstract/221/12/e202205051/213539/Nuclear-tension-controls-mitotic-entry-by
#BioMechanics #MechanoBiology #NuclearTension #CellBiology #CellCycle #CellDivision #NuclearEnvelope #NuclearTranslocation #CellCompression #GenomicInstability

Some hashtags of my interests to help people searching for follows (who knew how hard it was to do this without an algorithm feeding you content?)

#cellbiology #biophysics #microscopy #imageanalysis #cell #mitosis #celldivision #cytoskeleton #evolution #evocell #amoeba #cellmigration #jazz #nature #sciencemastodon #softmatter

Referenced link: https://phys.org/news/2022-07-key-asymmetric-cell-division-immortality.html
Discuss on https://discu.eu/q/https://phys.org/news/2022-07-key-asymmetric-cell-division-immortality.html

Originally posted by Phys.org / @physorg_com@twitter.com: https://twitter.com/physorg_com/status/1552652195199213569#m

A key process in asymmetric #celldivision preserves the immortality of the germline @ScienceAdvances https://www.science.org/doi/10.1126/sciadv.abo4443 https://phys.org/news/2022-07-key-asymmetric-cell-division-immortality.html

Referenced link: https://phys.org/news/2022-07-reveals-free-radicals-cell-division.html
Discuss on https://discu.eu/q/https://phys.org/news/2022-07-reveals-free-radicals-cell-division.html

Originally posted by Phys.org / @physorg_com@twitter.com: https://twitter.com/physorg_com/status/1552289509546799104#m

New study reveals how '#freeradicals' drive #celldivision, uncovering a potential new way to target cancer @icrnews https://linkinghub.elsevier.com/retrieve/pii/S1534580722004488 https://phys.org/news/2022-07-reveals-free-radicals-cell-division.html

Referenced link: https://phys.org/news/2022-06-uncovering-molecular-machinery-chromosomes-cell.html
Discuss on https://discu.eu/q/https://phys.org/news/2022-06-uncovering-molecular-machinery-chromosomes-cell.html

Originally posted by Phys.org / @physorg_com@twitter.com: https://twitter.com/physorg_com/status/1532673137262923776#m

Uncovering the inner workings of the molecular machinery that shapes chromosomes during #celldivision @sciencemagazine https://www.science.org/doi/10.1126/science.abm4012 https://phys.org/news/2022-06-uncovering-molecular-machinery-chromosomes-cell.html

Referenced link: https://phys.org/news/2022-05-key-protein-cell-division-puzzles.html
Originally posted by Phys.org / @physorg_com@twitter.com: https://twitter.com/physorg_com/status/1525130613803687936#m

Structure of key #protein for #celldivision puzzles researchers @MolecularCell https://doi.org/gp5frq https://phys.org/news/2022-05-key-protein-cell-division-puzzles.html

Referenced link: https://medicalxpress.com/news/2022-05-covid-deaths-elderly-due-genetic.html
Originally posted by Phys.org / @physorg_com@twitter.com: https://twitter.com/medical_xpress/status/1522853954983448586#m

RT by @physorg_com: #Model finds COVID-19 deaths among elderly may be due to genetic limit on #celldivision https://doi.org/gp4dxc https://medicalxpress.com/news/2022-05-covid-deaths-elderly-due-genetic.html