My Dresden colleagues have recently published a paper.

Carlotta Mayer (@c_ma_yer on the cross site) shows that #hepatocytes react to increased #bile #pressure by forming the #apical projections called bulkheads. This is also observed in #human #liver when bile pressure is increased to a pathological level. Upon further increase of bile pressure, bulkheads no longer hold the #canaliculi shape and form #rosettes.
#CellBiology #CellPolarity

https://doi.org/10.15252/embr.202357181

https://twitter.com/ZerialLab/status/1686028788658847744?s=20

RT @LaanLiedewij
Check out this perspective by my PhD Marieke about the evolution of self organizing systems, using #cellpolarity in budding yeast as an example, and ending with how self-organisation can complement selection as ordening principle.

https://journals.biologists.com/jcs/article/136/2/jcs259639/286742/Complexity-and-self-organization-in-the-evolution.