A new #mRNA technology developed at #Yale Cancer Center for the first time allows massively parallel #DNA substitutions into human cells.
In a study published in Nature Biotechnology this month, researchers used the new tech – named #CLASH – to quickly generate tens of thousands of #TCell variants and choose the best ones for use in #celltherapy for #cancer treatment.
https://medicine.yale.edu/news-article/yale-scientists-enable-massively-parallel-dna-insertions-into-human-cells/
#mrna #yale #dna #clash #TCell #celltherapy #cancer
Just Published!
Adoptive Cell Transfer for Solid Tumors
https://link.springer.com/chapter/10.1007/16833_2022_105
#Cancer #CancerResearch #CancerTherapy #CellBiology #CellTherapy
#cancer #cancerresearch #cancertherapy #cellbiology #celltherapy
New publication 🥳 We identify distinct molecular and anatomical changes in mouse models of immune deficiency after #stroke. These findings are important for developing new preclinical #CellTherapy to the brain