The EMBO Journal · @embojournal
525 followers · 260 posts · Server sciencemastodon.com
Extra #centrosomes are initially anti-#tumorigenic but why?
Irmina Garcia-Carpio, Andreas Villunger et al find that through #PIDDosome activation, they not only induce #p53 responses, but also #NFkB signaling to increase #immunogenicity of cancer cells
https://www.embopress.org/doi/full/10.15252/embj.2023113510
#centrosomes #tumorigenic #piddosome #P53 #nfkb #immunogenicity
The EMBO Journal · @embojournal
489 followers · 229 posts · Server sciencemastodon.com
Centrosome linker diversity: #Ninein, #Rootletin & #CNap1 contribute specific functions to #centrosome clustering and spindle formation, some of which matter in cells with extra #centrosomes
Laura Theile, Xue Li, Elmar Schiebel et al #UniHeidelberg
https://www.embopress.org/doi/full/10.15252/embj.2021109738
#ninein #rootletin #cnap1 #centrosome #centrosomes #uniheidelberg
Priti Atmakuru · @priti_atmakuru
75 followers · 52 posts · Server mstdn.socialSpindle in dividing cells,
single when it sleeps.
Bids goodbye in fusing cells,
so many secrets to reveal!
Our Opinion on the cilium-centrosome axis buzzing with activity during fate choice! Now @J_Cell_Sci
#cilia #centrosomes #centriolarsatellites #RNA
https://journals.biologists.com/jcs/article-abstract/136/9/jcs260454/308872/The-cilium-centrosome-axis-in-coupling-cell-cycle?redirectedFrom=fulltext
#RNA #centriolarsatellites #centrosomes #cilia
Mill_lab · @Mill_lab
367 followers · 229 posts · Server mstdn.socialWelcome to the #Fediverse @BazziLab :blobfoxwave: ! Glad you are here! #Cilia #Centrioles #Centrosomes #DevBiol #Mouse
#mouse #devbiol #centrosomes #centrioles #cilia #Fediverse
Mill_lab · @Mill_lab
548 followers · 492 posts · Server mstdn.socialWelcome to the #Fediverse @BazziLab :blobfoxwave: ! Glad you are here! #Cilia #Centrioles #Centrosomes #DevBiol #Mouse
#mouse #devbiol #centrosomes #centrioles #cilia #Fediverse
Tim Stearns · @StearnsLab
1155 followers · 166 posts · Server mas.to
We know that #centrosomes are not required for mitotic division, so what are they good for?
New preprint from grad student KC Farrell shows that having two duplicated centrosomes at the beginning of #mitosis facilitates rapid bipolar spindle formation. In the absence of centrosomes there is a checkpoint-mediated delay that is required to give enough time to sort things out and assemble the spindle.
#CellBiology
https://www.biorxiv.org/content/10.1101/2022.11.08.515699v1.full.pdf
#cellbiology #Mitosis #centrosomes
Tim Stearns · @StearnsLab
1155 followers · 166 posts · Server mas.to
#introduction
Hello #ScienceMastodon community!
I am a professor at Rockefeller University in #NYC and dean of the graduate school. Interested in all things #science, but especially #CellBiology, #centrosomes, #cilia, #CellCycle, the #cytoskeleton and #microscopy.
I also want to make science a better place for students and postdocs, and am interested in science education, outreach, publishing and policy. #ScienceEducation
Occasional infrared and film #photography posts to keep it interesting
#scienceeducation #microscopy #photography #science #cellbiology #cellcycle #ScienceMastodon #Cilia #centrosomes #nyc #cytoskeleton #introduction