Defeating all odds & ending year 3 on a no #cholangiocarcinoma high! Every post-cancer scan we reflect on the statistical survival rate & realise our #MedicalMiracle is due to one doctor who wasn't happy until they got to the bottom of it. We will send her a card & let her know.

RT @MPishvaian
@hopkinskimmel #HopkinsGI
🤔What are your💭on this debate - would you prefer to give neoadjuvant (or peri-adjuvant) chemotherapy
OR
only adjuvant chemotherapy for a resectable intrahepatic #cholangiocarcinoma
➡️@MarkYarchoan and Tom Karasic (from UPENN) are debating🗣️this now

RT @MPishvaian
#TumorBoardTuesday #GI23
🫤There were a few WELL DONE studies with results that were unexpectedly⛔️
➡️@DrAngelaLamarca, et al evaluated #cholangiocarcinoma patients treated with platinum therapy
👉There was NOT any difference in mOS when comparing DDR-WT vs. DDR-mut tumors😔

RT @MPishvaian
#TumorBoardTuesday #GI23
🫤There were a few WELL DONE studies with results that were unexpectedly⛔️
➡️@DrAngelaLamarca, et al evaluated #cholangiocarcinoma patients treated with platinum therapy
👉There was NOT any difference in mOS when comparing DDR-WT vs. DDR-mut tumors😔

RT @MPishvaian
@rafee_talukder @TumorBoardTues @PGrivasMDPhD @JohnEbbenMDPhD @MattGalsky @DrRosenbergMSK @JonAnker1 @shilpaonc #TumorBoardTuesday

~50% - wow😲

🤔Are there data on the kinds of alterations?
➡️In #cholangiocarcinoma, for example, only FGFR-fusions respond to FGFR⛔️

RT @MPishvaian
@rafee_talukder @TumorBoardTues @PGrivasMDPhD @JohnEbbenMDPhD @MattGalsky @DrRosenbergMSK @JonAnker1 @shilpaonc #TumorBoardTuesday

~50% - wow😲

🤔Are there data on the kinds of alterations?
➡️In #cholangiocarcinoma, for example, only FGFR-fusions respond to FGFR⛔️

https://pubmed.ncbi.nlm.nih.gov/36382577/ “The multidisciplinary management of #cholangiocarcinoma” #PalliativeCare is one discipline not included in this detailed, albeit biologically reductionistic, review. Nor is there any consideration re: goals of care, communication, or #hospice, end of life care. A major oversight. #cancer #oncology #PallOnc

I was blogging at the time of Dad’s illness, he loved the idea that others could hear more about his treatment and rare cancer.

I also blogged about his death, I wish we talked about it more. It was lengthy but peaceful.

I’ve connected with a number of people over the years who’ve found those blogs helpful, always surprises me.

Dad’s eulogy is here https://georgeblogs.wordpress.com/2012/12/07/george-robert-julian-eulogy/ on the off chance anyone fancies a read.

#cholangiocarcinoma #cancer #fuckcancer #death #dying

My brilliant Dad lived with bile duct cancer for the last 5yrs of his life. He took early retirement, we had a party for his 60th birthday and he turned yellow.

Initially he blamed the olives (true story) but then it worsened, we discovered it was jaundice and his bile ducts were blocked.

He had mostly great care from the NHS, a marathon op that lasted over 12hrs, chemo, we thought he was in remission, briefly, but it wasn’t to be.

#cholangiocarcinoma #cancer

RT @headlighty@twitter.com

The @CCA_Alliance@twitter.com aims to establish a global voice for #cholangiocarcinoma – support them by signing the GCA pledge today & share it #BileDuctCancer http://globalccaalliance.com/en/get-involved/the-pledge

🐦🔗: https://twitter.com/headlighty/status/1589922860063424512