A new fascinating hypothesis about the #Alzheimersdisease:

A study has linked #APOE4 [gene variant] with faulty #cholesterol processing in the #brain, which in turn leads to defects in the insulating sheaths that surround nerve fibres and facilitate their electrical activity. ...These changes could cause #memory and #learning deficits.
Drugs that restore the brain’s cholesterol processing could treat the disease.

#CholesterolTrafficJam
#Alzheimersgene #Alzheimer
https://www.nature.com/articles/d41586-022-03724-2