The #SuprachiasmaticNucleus (SCN) is a central clock, coordinating an animal's rhythmicity. This study reveals that AVP neurons in the #SCN are the main determinant of period, regulating other SCN neurons, and influencing #circadian rhythms #PLOSBiology https://plos.io/44tP8yM

Postdoctoral fellow in circadian biology

University of California, Davis

A time to plant, a time to reap, a time to #splice. . . . Help us learn how the #circadian clock interacts with fundamental cellular processes!

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-california-davis-27778-postdoctoral-fellow-in-circadian-biology/?feed_id=56812

...
https://jobrxiv.org/job/university-of-california-davis-27778-postdoctoral-fellow-in-circadian-biology/?feed_id=56812

How & why are #circadian rhythms maintained in red blood cells? Novel #haemoglobin #oxidation assay reveals it to be linked to body temperature regulation
A #RefereedPreprint c/o @ReviewCommons by John O‘Neill, Michael Hastings and coworkers
https://www.embopress.org/doi/full/10.15252/embj.2023114164

Postdoctoral fellow in circadian biology

University of California, Davis

A time to plant, a time to reap, a time to #splice. . . . Help us learn how the #circadian clock interacts with fundamental cellular processes!

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-california-davis-27778-postdoctoral-fellow-in-circadian-biology/?feed_id=53202

...
https://jobrxiv.org/job/university-of-california-davis-27778-postdoctoral-fellow-in-circadian-biology/?feed_id=53202

Postdoctoral fellow in circadian biology

University of California, Davis

A time to plant, a time to reap, a time to #splice. . . . Help us learn how the #circadian clock interacts with fundamental cellular processes!

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-california-davis-27778-postdoctoral-fellow-in-circadian-biology/?feed_id=52513

...
https://jobrxiv.org/job/university-of-california-davis-27778-postdoctoral-fellow-in-circadian-biology/?feed_id=52513

📰 "Alcohol sensitivity and tolerance encoding in sleep regulatory circadian neurons in Drosophila"
by 🔬 Anthony P Lange, Fred W Wolf
https://pubmed.ncbi.nlm.nih.gov/37500483/ #Drosophila #Circadian
#Sleep

Join our BioRDM team in #Edinburgh, as a Research Data Assistant. #Jobs We'll soon start to score #datasharing and support FAIR practices, with the MRC-funded #Circadian and #MentalHealth Network. Flexible work with a great team!
➡️ https://elxw.fa.em3.oraclecloud.com/hcmUI/CandidateExperience/en/job/7796

A #research area can Arrive by answering its main questions and showing how they matter. If your area has Arrived, you could consider a refocus on Settling rather than continuing the journey (here, of Discovery rather than economic Growth).

I argue that Chronobiology has Arrived. Hence one aim of our new research community organisation, BioClocks UK, is to use what we've learned, especially about #circadian biological clocks:
➡️ https://bioclocks.uk 3/4

@MShahand
Really cool work! I was very excited by this work when it arrived @flypapers
( https://botsin.space/@flypapers/110665669360876450 )
and mentioned that to Ezio and Bambos @NeurogeneticsLeicester22: very nice to see that Pdf is under selection as it is still by far the most studied neuropeptide in #circadian behaviour in #drosophila!

How about some structural circadian biology to end the week? The Partch lab, Thoma lab et al demonstrate how CLOCK:BMAL1 binds DNA in the context of histones, and show some rather elegant and surprising molecular interactions:

https://www.nature.com/articles/s41586-023-06282-3

#circadian
#structuralbiology
#cryoem

How the internal clock of our #cells is influenced by #mechanical forces.

#circadian #YAPprotein

https://phys.org/news/2023-07-internal-clock-cells-mechanical.html

Association between #circadian skin #temperature rhythms and actigraphic #sleep measures in real-life settings

Distal skin temperature with lower fluctuations and higher regularity and rhythm amplitudes was associated with better sleep quality. Our results could be applied in chronobiological interventions to improve sleep quality.
https://jcsm.aasm.org/doi/10.5664/jcsm.10590

Results strongly suggest the gut-#brain axis mediated hippocampal #circadian rhythm changes involved in the neurotoxicity of PS-NPs. #Melatonin or #probiotics supplementation may have the application value in the prevention of neurotoxicity of PS-NPs.
https://www.sciencedirect.com/science/article/abs/pii/S0304389423012323

New #PLOSBiology study shows that knockdown of the alternative polyadenylation factor CPSF6 affects the resilience of the #circadian free-running period against changes in environmental temperature in human cells https://plos.io/42Z8X09

Quantas Airlines Attacking Jet Lag:
Qantas has been studying how to make that journey more pleasant and the aftermath more bearable by instituting measures to reduce jet lag.#quantas #jetlag #circadian #sleep #tryptophan
https://youtu.be/lZZ5W0i4KX0

@YumiNakadera
Very interesting! Are they captivated or wild caught snails? Wondering if you sample the leaves with shorter time intervals, would the eating exhibit #circadian rhythm? Asynchronous feeding rhythm may explain the variation of leave intake?

📰 "The Emergence of Circadian Timekeeping in the Intestine"
by 🔬 Parasram, K., Zuccato, A., Shin, M., Willms, R., Deveale, B., Foley, E., Karpowicz, P.
http://biorxiv.org/content/10.1101/2023.06.06.543952v1?rss=1 #DrosophilaMelanogaster
#Drosophila #Circadian
#Adult

A simplified method to assess the #synchronization properties of the body #clock.

#signalling #circadian

https://phys.org/news/2023-06-method-synchronization-properties-body-clock.html

📰 "Restoration of sleep and circadian behavior by autophagy modulation in Huntington's disease"
by 🔬 Ankit Sharma, Kavyashree N, Ravi Manjithaya, Vasu Sheeba
https://pubmed.ncbi.nlm.nih.gov/37268416/ #Drosophila #Circadian
#Sleep

#Circadian control of white and brown adipose tissues

• Adipose tissues show strong circadian rhythm with implications for cardiometabolic health.
• Time of day should be considered when studying or targeting adipose function.
• Defining the molecular switches in circadian adipose function may yield novel therapeutic targets.

https://www.sciencedirect.com/science/article/pii/S0959437X23000369