It is much more difficult to do an cohort study well vs. an RCT. People forget that the into cohort matters & that assessments are more difficult (if outright impossible) with , esp if you don't/won't grasp the mechanics of cohort generation.

#observational #selection #causal #cohorts #biostatistics #epidemiology #clinicalresearch #clinicaltrials

Last updated 1 year ago

TU München · @tu_muenchen
324 followers · 219 posts · Server wisskomm.social

Our university, the LMU, the associated hospitals and Helmholtz Munich signed a letter of intent to establish a new medical alliance called "M1 - Munich Alliance": go.tum.de/450886

📷A. König

#medicine #clinicalresearch #medicalinfrastructure

Last updated 1 year ago

TanyaAneichyk · @tanyaaneichyk
56 followers · 46 posts · Server genomic.social

When validating your therapeutic target, don't forget to check whether there is a commonly occurring non-pathogenic mutation that may impair your intended MoA!

OmicsChart

#targetdiscovery #DrugDiscovery #oncology #omicschart #clinicalresearch

Last updated 1 year ago

What the hell is the point of getting central approval for a non-interventional, de-identified registry if every site insists on getting local approval anyway?

Not that it’s not a joy to work with IRBs at 15 institutions who are all asking variations of the exact same questions, mind you.

This nonsense repeatedly pushes out the date by which this registry can be used to help people with aggressive , and these folks don't have a lot of time to spare. 🤬

#irb #blood #cancer #clinicalresearch

Last updated 1 year ago

Tech news from Canada · @TechNews
680 followers · 20171 posts · Server mastodon.roitsystems.ca
PastelBio · @pastelbio
132 followers · 1109 posts · Server mstdn.science

RT @: in cell biology and disease mechanisms
Oct 25-27th, Heidelberg
In-person and
Abstract submission deadline - Aug 8th
embl.org/about/info/course-and via @embl

#proteomics #virtual #TeamMassSpec #clinicalresearch #conference

Last updated 1 year ago

TrangAston :verified: · @CastlTrAstonDrs
1280 followers · 2509 posts · Server med-mastodon.com

Investigate the effect of psychological capital on alienation among patients with and the mediating role of social support in this relationship.
virologyj.biomedcentral.com/ar

#IDMastodon #psychology #clinicalresearch #COVID19

Last updated 1 year ago

EASE · @EASE
64 followers · 31 posts · Server mstdn.science

The Lancet are using the SAGER guidelines (ease.org.uk/communities/gender) to improve sex and gender reporting in abstracts, introductions, tables, and adverse events, says Joan Marsh.

They're also asking authors about their choice of outcome measures: why used, how widely used, is it accessible or proprietary, clinical significance?

#easeevents #journalediting #sexandgender #clinicalresearch

Last updated 1 year ago

Acta Médica Portuguesa · @amp
5 followers · 55 posts · Server masto.pt

AMP has just published!
"The Challenges of Setting Up a Clinical Study with the New European Union Medical Device Regulation"

Perspective Article by Sílvia Rêgo, Marco Dutra-Medeiros and Francisco Nunes - a multicenter work.

Full paper available here:
actamedicaportuguesa.com/revis

#clinicalresearch #europeanunion #medicaldevicelegislation

Last updated 1 year ago

MJ Muse · @MJmusicinears
467 followers · 5360 posts · Server mastodon.world

cbc.ca/radio/asithappens/as-it Scientists discover a man leading a normal life with 90% of his brain missing. A 44-year-old man from France started experiencing weakness in his leg, he went to the hospital. That's when doctors told him he was missing most of his brain. The man's skull was full of liquid, with just a thin layer of brain tissue left.

#mastodonscience #psychology #clinicalresearch

Last updated 2 years ago

Yan Leyfman, MD · @yleyfman
126 followers · 220 posts · Server med-mastodon.com
Yan Leyfman, MD · @yleyfman
126 followers · 219 posts · Server med-mastodon.com
John Grimes · @johngrimes
6 followers · 25 posts · Server fosstodon.org

Here's a short presentation I made at the recent AEHRC Colloquium: youtu.be/JUODmNFEL88

It takes you through a few examples of using Pathling to query the ontological features of SNOMED codes within your data analysis.

#healthdata #clinicalresearch #SnomedCT

Last updated 2 years ago

Yan Leyfman, MD · @yleyfman
126 followers · 214 posts · Server med-mastodon.com

RT @PCORnetwork
Reminder for & professionals: @PCORI has added a Category 3 to the Broad Pragmatic Studies (BPS) PCORI Funding Announcement. This will support studies that advance PCORI’s National Priorities for Health. Learn more: bit.ly/3JhOywz

#clinicalresearch #healthcare #pcornet

Last updated 2 years ago

UKRIO · @ukrio
362 followers · 250 posts · Server mstdn.science

Reading Clinical Studies: Taking off the rose colored glasses and the peril if we don’t. Today, 5pm, by Consilium Scientific.

Prof Nathan Cherny on systematic critical evaluation of clinical studies to find common biases in oncology research:
1. Surrogate endpoints
2. Study design & implementation that exaggerate survival
3. Post hoc & subgroup analyses, confirmatory vs conjectural findings

consilium-scientific.us10.list

#clinicalresearch #CriticalAppraisal #howtoreadapaper #webinar #MedMastodon

Last updated 2 years ago

Alex 🌍 🍁 · @AlexKarabanow
227 followers · 2523 posts · Server mastodon.social
Yan Leyfman, MD · @yleyfman
125 followers · 183 posts · Server med-mastodon.com
Patient Advocate & artist · @lymphomation
162 followers · 696 posts · Server mastodon.social


@majorajay

Dual targeting of CD19 and CD22 with Bicistronic CAR-T cells in Patients with Relapsed/Refractory Large B Cell Lymphoma

pubmed.ncbi.nlm.nih.gov/368217

#MedMastodon #lymphoma #cancer #clinicalresearch #oncology #medicine #lymsm

Last updated 2 years ago

Alex 🌍 🍁 · @AlexKarabanow
225 followers · 2484 posts · Server mastodon.social

‘It’s perfect’: World’s first generative AI-designed COVID drug to start clinical trials

#ResearchEthics #AI #ClinicalResearch #COVID #COVIDTreatment

thestar.com/news/canada/2023/0

#researchethics #ai #clinicalresearch #covid #CovidTreatment

Last updated 2 years ago