Reminder to pick your outcomes.

Vancomycin vs Fidaxomicin in #Cdiff- same mortality, but lower recurrence with fidaxo
#Clostridiumdifficile #antibiotics #microbiology #IDMastodon #infectiousdeseases

The Effect of Antibiotic Therapy for Clostridioides difficile Infection on Mortality and Other Patient-Relevant Outcomes: a Systematic Review and Meta-analysis - Clinical Microbiology and Infection https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(23)00420-2/fulltext

Oh good, cos this is exactly what we do.

In #Clostridiumdifficile diarrhoea, we treat NAAT+ve, / toxin - ve if they have #diarrhea and no obvious reason for it.

#IDMastodon #MedMastodon #medicine #infectiousdiseases

Clinical Outcomes and Management of NAAT-Positive/Toxin-Negative Clostridioides difficile Infection: A Systematic Review and Meta-Analysis | Clinical Infectious Diseases | Oxford Academic

https://academic.oup.com/cid/advance-article-abstract/doi/10.1093/cid/ciad523/7256092

Any transplantation carries a risk of infection transmission. Concern that faecal transplantation may 👉 H pylori transmission.

Not from this (small) case series. Also needs saying that faeces were screened for antigen, which ≭ live organism.

#IDMastodon #MedMastodon #transplant #feces #Clostridiumdifficile

https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(23)00081-2/fulltext?dgcid=raven_jbs_aip_email

Any transplantation carries a risk of infection transmission. Concern that faecal transplantation may 👉 H pylori transmission.

Not from this (small) case series. Also needs saying that faeces were screened for antigen, which ≭ live organism.

#IDMastodon #MedMastodon #transplant #feces #Clostridiumdifficile

Risk of Helicobacter pylori transmission by faecal microbiota transplantation via oral capsules - Clinical Microbiology and Infection

https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(23)00081-2/fulltext?dgcid=raven_jbs_aip_email

The latest The antimicrobial stewardship Daily! https://paper.li/MicrobLog_me_uk/1574020423?edition_id=93fb0710-9057-11ed-9537-fa163e6ccaff Thanks to @DMU_CCSR@twitter.com @VirtualOutcome1@twitter.com @TorontoStar@twitter.com #opinion #clostridiumdifficile

Prescription poop is here: FDA approves fecal slurry for unshakeable diarrhea by Beth Mole

Fri, 02 Dec 2022 00:38:57 +0000

https://arstechnica.com/?p=1901516

#Science #CDiff #ClinicalTrial #ClostridiumDifficile #Enema #Fda #FecalTransplant #Ferring #Fmt #Infection #Microbes #Microbiome #Rebyota

Prescription poop is here: FDA approves fecal slurry for unshakeable diarrhea - Enlarge / Laboratory technicians in France prepare stool to treat patie... - https://arstechnica.com/?p=1901516 #clostridiumdifficile #fecaltransplant #clinicaltrial #microbiome #infection #microbes #science #ferring #rebyota #c.diff #enema #fda #fmt

@mikadojoe
À ce jour la #BactériothérapieFécale (#FMT) est efficace uniquement contre la #ColitePseudoMembraneuse due à #ClostridiumDifficile (#CDI).

Pour les autres colites, notamment la #ColiteUlcéreuse (#RCH ou #UC), ce n’est que de la #recherche heuristique.
Infructueuse d’ailleurs de l’avis (récent) de #ThomasBorody, un de ses plus importants promoteurs.

« Unlike CDI, the use of FMT in UC can result in transient improvement but only very occasionally—in a cure. »
http://pamw.pl/sites/default/files/inv_rev_Borody_ONLINE.pdf